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Synthesis and screening for anticancer activity of two novel telluro-amino acids: 1,3-Tellurazolidine-4-carboxylic acid and tellurohomocystine

期刊: AMINO ACIDS, 2023; 55 (10)

Tellurium (Te) containing amino acids and their derivatives have the potential to participate in biological processes, which are currently being studi......

Altered kynurenine pathway metabolism and association with disease activity in patients with systemic lupus

期刊: AMINO ACIDS, 2023; 55 (12)

Systemic lupus erythematosus (SLE) is an autoimmune disease accompanied by increased release of proinflammatory cytokines that are known to activate t......

PTPAMP: prediction tool for plant-derived antimicrobial peptides

期刊: AMINO ACIDS, 2023; 55 (1)

The emergence of antimicrobial peptides (AMPs) as a potential alternative to conventional antibiotics has led to the development of efficient computat......

Determination of equilibria constants of arginine:glycine amidinotransferase (AGAT)-catalyzed reactions using concentrations of circulating amino acids

期刊: AMINO ACIDS, 2023; 55 (2)

Arginine:glycine amidinotransferase (AGAT) catalyzes mainly two reactions that generate 1) L-homoarginine (hArg) from L-arginine and L-lysine (K-harg)......

Age-associated polyamines in peripheral blood cells and plasma in 20 to 70 years of age subjects

期刊: AMINO ACIDS, 2023; 55 (6)

Dietary polyamines have been associated with slowing ageing processes and various pathologies, raising the importance of establishing reference values......

Covalent-reversible peptide-based protease inhibitors. Design, synthesis, and clinical success stories

期刊: AMINO ACIDS, 2023; 55 (12)

Dysregulated human peptidases are implicated in a large variety of diseases such as cancer, hypertension, and neurodegeneration. Viral proteases for t......

Effect of lipopeptide extracted from Bacillus licheniformis on the expression of bap and luxI genes in multi-drug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

期刊: AMINO ACIDS, 2023; 55 (12)

Recently, opportunistic pathogens like Acinetobacter baumannii and Pseudomonas aeruginosa have caused concern due to their ability to cause antibiotic......

In silico analysis of the possible crosstalk between O-linked β-GlcNAcylation and phosphorylation sites of Disabled 1 adaptor protein in vertebrates

期刊: AMINO ACIDS, 2023; 55 (6)

Disabled 1 (Dab1) is an adaptor protein with essential functions regulated by reelin signaling and affects many biological processes in the nervous sy......

Serum branched amino acids and the risk of all-cause mortality: a meta-analysis and systematic review

期刊: AMINO ACIDS, 2023; 55 (11)

Recently, the serum levels of branched-chain amino acids (BCAAs) have been considered as an indicator to evaluate health status and predict chronic di......

Chromogranin A-derived peptides pancreastatin and catestatin: emerging therapeutic target for diabetes

期刊: AMINO ACIDS, 2023; 55 (5)

Chromogranin A (ChgA) is an acidic pro-protein found in neuroendocrine organs, pheochromocytoma chromaffin granules, and tumor cells. Proteolytic proc......

Screening of AS101 analog, organotellurolate (IV) compound 2 for its in vitro biocompatibility, anticancer, and antibacterial activities

期刊: AMINO ACIDS, 2023; 55 (7)

Organotellurium compounds are being well researched as potential candidates for their functional roles in therapeutic and clinical biology. Here, we r......

Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence

期刊: AMINO ACIDS, 2023; 55 (10)

Guanidino compounds such as dimethylarginines (SDMA, ADMA) and L-homoarginine ((L-)hArg) can interfere with bioavailability and function of the main N......

Enzymatically modified isoquercitrin in soy protein temporarily enhanced the plasma amino-acid concentrations, antioxidant index, and plasma hormone levels: a randomized, double-blind cross-over trial

期刊: AMINO ACIDS, 2023; 55 (6)

This study investigated the effects of a dietary protein supplement containing enzymatically modified isoquercitrin (EMIQ) on plasma amino-acid levels......

P19-derived neuronal cells express H1, H2, and H3 histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents

期刊: AMINO ACIDS, 2023; 55 (6)

Histamine is a biogenic amine implicated in various biological and pathological processes. Convenient cellular models are needed to screen and develop......

The renoprotective effects of taurine against diabetic nephropathy via the p38 MAPK and TGF-β/Smad2/3 signaling pathways

期刊: AMINO ACIDS, 2023; 55 (11)

Diabetic nephropathy (DN), a severe diabetes complication, causes kidney morphological and structural changes due to extracellular matrix accumulation......

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