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Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway

期刊: AUTOIMMUNITY, 2023; 56 (1)

This study was conducted to investigate the effect and underlying mechanism of endonuclease G (ENDOG) on preeclampsia (PE). Differentially expressed g......

Highly-expressed circ_0129657 inhibits proliferation as well as promotes apoptosis and inflammation in HBMECs after oxygen-glucose deprivation via miR-194-5p/GMFB axis

期刊: AUTOIMMUNITY, 2023; 56 (1)

Stroke is an acute cerebrovascular disease that is now the most important cause of death due to brain problems in our country. CircRNAs are RNA circle......

DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls

期刊: AUTOIMMUNITY, 2023; 56 (1)

We elucidated the effect of four known T1D-susceptibility associated single nucleotide polymorphism (SNP) markers in three genes (rs12722495 and rs210......

LncRNA DGCR5/miR-204-5p/SRSF7 axis regulates PDGF-BB-induced proliferation and migration of airway smooth muscle cells with potential role in asthma

期刊: AUTOIMMUNITY, 2023; 56 (1)

Increased proliferation and migration of abnormal airway smooth muscle cells (ASMCs) are significantly associated with asthma. Recently, the function ......

Patients with dermatomyositis shared partially similar transcriptome signature with COVID-19 infection

期刊: AUTOIMMUNITY, 2023; 56 (1)

Dermatomyositis (DM) is an autoimmune disease that primarily affects the skin and skeletal muscle. Virus infection and type I interferon-related signa......

Zinc finger protein 189 promotes the differentiation of lamina propria T helper 17.1 cells in dextran sulfate sodium-induced colitis

期刊: AUTOIMMUNITY, 2023; 56 (1)

The factors regulating the heterogeneity of interleukin-17A (IL-17A)-expressing CD4(+) T cells in inflammatory bowel diseases remain unclear. In the c......

Effects of Apelin on the fibrosis of retinal tissues and Muller cells in diabetes retinopathy through the JAK2/STAT3 signalling pathway

期刊: AUTOIMMUNITY, 2023; 56 (1)

Retinal fibrosis was a key characteristic of diabetes retinopathy (DR). Apelin was found to be a candidate for tissue fibrosis. Nevertheless, the role......

Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis

期刊: AUTOIMMUNITY, 2023; 56 (1)

Lupus nephritis (LN) is a major cause death in patients with systemic lupus erythematosus. We aimed to find the differentially expressed genes (DEGs) ......

Isorhynchophylline attenuates proliferation and migration of synovial fibroblasts via the FOXC1/β-catenin axis

期刊: AUTOIMMUNITY, 2023; 56 (1)

Rheumatoid arthritis (RA) is a common type of chronic inflammatory disease. Elucidating the mechanism of fibroblast-like synovial (FLS) as a pathologi......

Circ_0006944 aggravates LPS-induced HK2 cell injury via modulating miR-205-5p/UBL4A pathway

期刊: AUTOIMMUNITY, 2023; 56 (1)

Circular RNAs (circRNAs) has been manifested to be involved in the development of human diseases, including sepsis-associated acute kidney injury (SA-......

Potential significance of changes in serum levels of IL-17, TNF-α and DKK-1 in the progression of the rheumatoid arthritis

期刊: AUTOIMMUNITY, 2023; 56 (1)

To detect the value of serum interleukin-17 (IL-17), tumour necrosis factor-alpha (TNF-alpha), and Dickkopf-1 (DKK-1) in rheumatoid arthritis (RA) at ......

Inhibition of LncRNA SNHG14 protects chondrocyte from injury in osteoarthritis via sponging miR-137

期刊: AUTOIMMUNITY, 2023; 56 (1)

Long-chain noncoding small nucleolar RNA host gene 14 (LncRNA SNHG14) is highly expressed in various diseases and promotes diseases progression, but t......

Oncolytic virus oHSV2 combined with PD-1/PD-L1 inhibitors exert antitumor activity by mediating CD4?+?T and CD8?+?T cell infiltration in the lymphoma tumor microenvironment

期刊: AUTOIMMUNITY, 2023; 56 (1)

A novel therapeutic regimen showed that the oncolytic type II herpes simplex virus (oHSV2) was able to prevent colorectal cancer growth, recurrence, a......

Mesenchymal stem cells-derived exosomes ameliorate high glucose and lipopolysaccharide-induced HPMECs injury through the Nrf2/HO-1 pathway

期刊: AUTOIMMUNITY, 2023; 56 (1)

Mesenchymal stem cells-derived exosomes (MSC-Exo) are considered to have great potential in the treatment of human diseases. However, the role of MSC-......

Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues

期刊: AUTOIMMUNITY, 2023; 56 (1)

Semaphorin 3A (Sema3A) is a secretory member of the semaphorin family of immune response regulators. This research focuses on its effects on inflammat......

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