期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (2)
Despite the remarkable advancement in the health care sector, cancer remains the second most fatal disease globally. The existing conventional cancer ......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
Over the course of three decades of study, the deubiquitinase Herpesvirus associated Ubiquitin-Specific Protease/ Ubiquitin-Specific Protease 7 (HAUSP......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
Metabolic plasticity, which determines tumour growth and metastasis, is now understood to be a flexible and context-specific process in cancer metabol......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
The tumour suppressor p53 is activated following genotoxic stress and regulates the expression of target genes involved in the DNA damage response (DD......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
Cancer is one of the leading causes of death worldwide, primarily due to the dearth of efficient therapies that result in long-lasting remission. This......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (5)
The Growth and Differential Factor 11 (GDF11) is a recently discovered representative of Transforming Growth Factor ss superfamily. The highest expres......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
Post-translational modifications (PTMs) are common covalent processes in biochemical pathways that alter protein function and activity. These modifica......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
The Warburg effect is a phenomenon in which cancer cells rely primarily on glycolysis rather than oxidative phosphorylation, even in the presence of o......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
Merkel cell carcinoma (MCC) is a rare cancer of the skin characterized by a neuroendocrine phenotype and an aggressive clinical behavior. It frequentl......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
The intricate molecular interactions leading to the oncogenic pathway are the consequence of cell cycle modification controlled by a bunch of cell cyc......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (3)
Cancer being the leading cause of mortality has become a great threat worldwide. Current cancer therapeutics lack specificity and have side effects du......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
The interest in finding new targets in the tumor microenvironment for anti-cancer therapy has increased rapidly over the years. More specifically, the......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
Treatment resistance, together with acute and late adverse effects, represents critical issues in the management of cancer patients. Promising results......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
ROR gamma T is a transcription factor that directs the development of Th17 lymphocytes and other IL-17-expressing cells (e.g., Tc17 and ILC3 cells). T......
期刊: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023; 1878 (6)
Nitric oxide (NO), a gaseous radical, governs a variety of physiological and pathological processes, including cancer, pro-inflammatory signalling, an......