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Extracellular signals regulate the biogenesis of extracellular vesicles

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With ......

JIF:5.093

Tellurite and Selenite: how can these two oxyanions be chemically different yet so similar in the way they are transformed to their metal forms by bacteria?

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

This opinion review explores the microbiology of tellurite, TeO32- and selenite, SeO32- oxyanions, two similar Group 16 chalcogen elements, but with s......

JIF:5.093

tiRNA-Val promotes angiogenesis via Sirt1-Hif-1 alpha axis in mice with diabetic retinopathy

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background: Diabetic retinopathy (DR) is a specific microvascular complication arising from diabetes, and its pathogenesis is not completely understoo......

JIF:5.093

Impact of inactivated SARS-CoV-2 vaccination on embryo ploidy: a retrospective cohort study of 133 PGT-A cycles in China

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Unsubstantiated concerns have been raised on the potential correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)......

JIF:5.093

Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineer......

JIF:5.093

Cobalamin cbiP mutant shows decreased tolerance to low temperature and copper stress in Listeria monocytogenes

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Listeria monocytogenes is a foodborne pathogen that causes listeriosis in humans. This pathogen activates multiple regulatory mechanisms in......

JIF:5.093

Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Tellurium is a rare metalloid that exerts high toxicity on cells, especially on bacteria, partly due to reactive oxygen species (ROS) gener......

JIF:5.093

Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV). Otolin, a secreted glycoprotein with......

JIF:5.093

Zinc oxide nanoparticles synthesized using Hyssopus Officinalis L. Extract Induced oxidative stress and changes the expression of key genes involved in inflammatory and antioxidant Systems

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Recent advances in the synthesis of bioactive nanoparticles resulted in the discovery and introduction of new bioactive nanoparticles to th......

JIF:5.093

The OxyR and SoxR transcriptional regulators are involved in a broad oxidative stress response in Paraburkholderia xenovorans LB400

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Aerobic metabolism generates reactive oxygen species that may cause critical harm to the cell. The aim of this study is the characterizatio......

JIF:5.093

Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Genetic modification of living organisms has been a prosperous activity for research and development of agricultural, industrial and biomedical applic......

JIF:5.093

Genetic regulation of the ompX porin of Salmonella Typhimurium in response to hydrogen peroxide stress

期刊: BIOLOGICAL RESEARCH, 2022; 55 (1)

Background Salmonella Typhimurium is a Gram-negative pathogen that causes a systemic disease in mice resembling typhoid fever. During its infective cy......

JIF:5.093

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