期刊： BIOORGANIC CHEMISTRY, 2023; 130 ()
A number of novel annulated pyrazolopyranopyrimidines were prepared via reaction of iminoether of the corresponding 6-amino-5-cyano-pyrano[2,3-c]pyraz......
期刊： BIOORGANIC CHEMISTRY, 2023; 135 ()
Ticlopidine is an antithrombotic prodrug of the thienotetrahydropyridine family. For platelet inhibition it has to undergo oxidative ring-opening by c......
期刊： BIOORGANIC CHEMISTRY, 2023; 138 ()
CtpF is a Ca2+ transporter P-type ATPase key to the response to stress conditions and to Mycobacterium tuber-culosis virulence, therefore, an interest......
期刊： BIOORGANIC CHEMISTRY, 2023; 139 ()
In this 21st century, Malaria remains a global burden and causes massive economic trouble to disease-endemic nations. The control and eradication of m......
期刊： BIOORGANIC CHEMISTRY, 2023; 139 ()
Though growing evidence has been collected in support of the concept of dose escalation based on the molecular level images indicating hypoxic tumor s......
期刊： BIOORGANIC CHEMISTRY, 2023; 139 ()
Tumor selectivity is yet a challenge in chemotherapy-based cancer treatment. A series of calixarenes derivatized at the lower rim with 3-phenyl-1H-pyr......
期刊： BIOORGANIC CHEMISTRY, 2023; 139 ()
Over the past decades, many cell-penetrating peptides (CPP) have been studied for their capacity to cross cellular membranes, mostly in order to impro......
期刊： BIOORGANIC CHEMISTRY, 2023; 140 ()
The study investigated the structure-activity relationship of newly synthesized dye-linker-macrocycle (DLM) conjugates and the effect of each componen......
期刊： BIOORGANIC CHEMISTRY, 2023; 141 ()
In the present study, the undescribed schitriterpenoids, kadsujanonols A-I (1-9), and eleven reported compounds (10-20) were isolated from K. japonica......
期刊： BIOORGANIC CHEMISTRY, 2023; 141 ()
Xeno nucleic acids (XNA) are an increasingly important class of hypermodified nucleic acids with great potential in bioorganic chemistry and synthetic......
期刊： BIOORGANIC CHEMISTRY, 2023; 130 ()
Cannabinoid receptor 1 (CB1) is a G protein-coupled receptor and a therapeutic target for metabolic disorders. Numerous CB1 antagonists have been deve......
期刊： BIOORGANIC CHEMISTRY, 2023; 132 ()
Tertiary phosphine oxides, phosphine sulfides, and phosphine selenides containing pyridine, imidazole, and pyrazole groups have been synthesized via t......
期刊： BIOORGANIC CHEMISTRY, 2023; 133 ()
Most of the currently available cytotoxic agents for tackling cancer are devoid of selectivity, thus causing severe side-effects. This situation stimu......
期刊： BIOORGANIC CHEMISTRY, 2023; 130 ()
Targeting vascular endothelial growth factor receptor (VEFGR) and its co-receptor neuropilin-1 (NRP-1) is an interesting vascular strategy. tLyp-1 is ......
期刊： BIOORGANIC CHEMISTRY, 2023; 130 ()
COVID-19 and associated substantial inflammations continue to threaten humankind triggering death world-wide. So, the development of new effective ant......
