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Quantifying uncertainty in spikes estimated from calcium imaging data

期刊: BIOSTATISTICS, 2023; 24 (2)

In recent years, a number of methods have been proposed to estimate the times at which a neuron spikes on the basis of calcium imaging data. However, ......

Multivariate Bayesian spatio-temporal P-spline models to analyze crimes against women

期刊: BIOSTATISTICS, 2023; 24 (3)

Univariate spatio-temporal models for areal count data have received great attention in recent years for estimating risks. However, models for studyin......

Spatial Difference Boundary Detection for Multiple Outcomes Using Bayesian Disease Mapping

期刊: BIOSTATISTICS, 2023; 24 (4)

Regional aggregates of health outcomes over delineated administrative units (e.g., states, counties, and zip codes), or areal units, are widely used b......

A flexible approach for predictive biomarker discovery

期刊: BIOSTATISTICS, 2023; 24 (4)

An endeavor central to precision medicine is predictive biomarker discovery; they define patient sub-populations which stand to benefit most, or least......

Differences in set-based tests for sparse alternatives when testing sets of outcomes compared to sets of explanatory factors in genetic association studies

期刊: BIOSTATISTICS, 2023; 25 (1)

Set-based association tests are widely popular in genetic association settings for their ability to aggregate weak signals and reduce multiple testing......

Inference after latent variable estimation for single-cell RNA sequencing data

期刊: BIOSTATISTICS, 2023; 25 (1)

In the analysis of single-cell RNA sequencing data, researchers often characterize the variation between cells by estimating a latent variable, such a......

Systematically missing data in causally interpretable meta-analysis

期刊: BIOSTATISTICS, 2023; ()

Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target ......

Nonparametric causal mediation analysis for stochastic interventional (in)direct effects

期刊: BIOSTATISTICS, 2023; 24 (3)

Causal mediation analysis has historically been limited in two important ways: (i) a focus has traditionally been placed on binary exposures and stati......

Tree-based subgroup discovery using electronic health record data: heterogeneity of treatment effects for DTG-containing therapies

期刊: BIOSTATISTICS, 2023; ()

The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. How......

Prognosis of cancer survivors: estimation based on differential equations

期刊: BIOSTATISTICS, 2023; 24 (2)

We present a method for estimating several prognosis parameters for cancer survivors. The method utilizes the fact that these parameters solve differe......

Identifying covariate-related subnetworks for whole-brain connectome analysis

期刊: BIOSTATISTICS, 2023; ()

Whole-brain connectome data characterize the connections among distributed neural populations as a set of edges in a large network, and neuroscience r......

Feature selection for support vector regression using a genetic algorithm

期刊: BIOSTATISTICS, 2023; 24 (2)

Support vector regression (SVR) is particularly beneficial when the outcome and predictors are nonlinearly related. However, when many covariates are ......

DeLIVR: a deep learning approach to IV regression for testing nonlinear causal effects in transcriptome-wide association studies

期刊: BIOSTATISTICS, 2023; ()

Transcriptome-wide association studies (TWAS) have been increasingly applied to identify (putative) causal genes for complex traits and diseases. TWAS......

Multiple imputation of more than one environmental exposure with nondifferential measurement error

期刊: BIOSTATISTICS, 2023; ()

Measurement error is common in environmental epidemiologic studies, but methods for correcting measurement error in regression models with multiple en......

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