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Assessing and managing medication overuse headache in Australian clinical practice

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

More than 3 million Australians are estimated to have migraine disorders, and over a quarter of a million Australians are estimated to have medication......

Out-of-hospital multimodal seizure detection: a pilot study

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (2)

BackgroundOut-of-hospital seizure detection aims to provide clinicians and patients with objective seizure documentation in efforts to improve the cli......

Leukoaraiosis and stroke severity scores in post-rtPA intracerebral haemorrhage

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (2)

IntroductionPost thrombolytic symptomatic intracerebral haemorrhage (sICH) is a major concern in patients who had acute ischaemic stroke. Leukoaraiosi......

Cerebral venous sinus thrombosis secondary to acute cytomegalovirus infection

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (2)

BackgroundCerebral venous sinus thrombosis (CVST) is a potentially life-threatening disorder with a number of causes, including viral infections.Case ......

Effects of blood pressure and tranexamic acid in spontaneous intracerebral haemorrhage: a secondary analysis of a large randomised controlled trial

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

Background Tranexamic acid reduced haematoma expansion and early death, but did not improve functional outcome in the tranexamic acid for hyperacute s......

Weight management communications in idiopathic intracranial hypertension: challenges and recommendations from the patients' perspective

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (2)

Background Idiopathic intracranial hypertension (IIH) is a neurometabolic condition severely impacting the quality of life of people living with IIH (......

Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

Background Neurofilament light (NfL) is a widely used biomarker for neurodegeneration. NfL is prone to oligomerisation, but available assays do not re......

Door-in-door-out times for patients with large vessel occlusion ischaemic stroke being transferred for endovascular thrombectomy: a Victorian state-wide study

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

BackgroundTime to reperfusion is an important predictor of outcome in ischaemic stroke from large vessel occlusion (LVO). For patients requiring endov......

Retinal vascular density in CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy)

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

Background and objectiveRetinal vascular density (VD) measured using optical coherence tomography with angiography (OCTA) has been suggested as a pote......

Evaluating the limits of AI in medical specialisation: ChatGPT's performance on the UK Neurology Specialty Certificate Examination

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

BackgroundLarge language models such as ChatGPT have demonstrated potential as innovative tools for medical education and practice, with studies showi......

Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared with the general population

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

BackgroundHomeless or precariously housed individuals live with poor health and experience premature mortality compared with the general population, y......

Muscle spindles as pain receptors

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

BackgroundMuscle membranes have a sensation of pain, but within the muscle tissue, the origin of pain is unclear. We present a hypothesis that the pai......

Efficacy of 48 hours dose of phenytoin in prevention of early post-traumatic seizure

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (1)

BackgroundAntiseizure medications, such as phenytoin sodium, have been shown in some reports to reduce the incidence of early post-traumatic seizure. ......

Valproate pregnancy prevention scheme: what are the barriers to enrolling patients and how do we meet them?

期刊: BMJ NEUROLOGY OPEN, 2023; 5 (2)

BackgroundThe UK Medicines Health products Regulation Agency instructs that valproate prescriptions should be restricted in women of childbearing age ......

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