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Evaluation and comparison of different breast cancer prognosis scores based on gene expression data

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundBreast cancer is one of the three most common cancers worldwide and is the most common malignancy in women. Treatment approaches for breast ......

METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundChemotherapy is an important strategy for the treatment of hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+H......

Impact of breast cancer care pathways and related symptoms on the return-to-work process: results from a population-based French cohort study (CONSTANCES)

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundBreast cancer (BC) treatments and related symptoms may affect return to work (RTW). The objective of this study was to investigate the impac......

Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundCell adhesion is indispensable for appropriate tissue architecture and function in multicellular organisms. Besides maintaining tissue integ......

On-treatment derived neutrophil-to-lymphocyte ratio and survival with palbociclib and endocrine treatment: analysis of a multicenter retrospective cohort and the PALOMA-2/3 study with immune correlates

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

Background Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors have been established as a standard treatment for hormone receptor (HR)-positive, human......

Expression of hormone receptors is associated with specific immunological profiles of the breast cancer microenvironment

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundElucidating the unique immunoregulatory mechanisms in breast cancer microenvironment may help develop new therapeutic strategies. Some studi......

Head-to-head comparison of perfluorobutane contrast-enhanced US and multiparametric MRI for breast cancer: a prospective, multicenter study

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundMultiparametric magnetic resonance imaging (MP-MRI) has high sensitivity for diagnosing breast cancers but cannot always be used as a routin......

Clinical evaluation of molecular surrogate subtypes in patients with ipsilateral multifocal primary breast cancer

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

BackgroundWhen ipsilateral multifocal primary breast cancer (IMBC) is detected, standard routine is to evaluate the largest tumor with immunohistochem......

Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms

期刊: BREAST CANCER RESEARCH, 2023; 25 (1)

Background Immunohistochemical (IHC) PD-L1 expression is commonly employed as predictive biomarker for checkpoint inhibitors in triple-negative breast......

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