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Menstrual abnormalities after COVID-19 vaccination in the Netherlands: A description of spontaneous and longitudinal patient-reported data

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (10)

AimsDuring the COVID-19 vaccination campaigns, the number of reports of menstrual abnormalities increased rapidly. Here, we describe the nature and po......

Movement disorders associated with antiseizure medications: A real-world disproportionality analysis of the Food and Drug Administration Adverse Event Reporting System

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (11)

AimsPatients with epilepsy often require long-term use of antiseizure medications (ASMs) to control their seizures. However, movement disorders (MDs) ......

Nongenetic and genetic predictors of haemodynamic instability induced by propofol and opioids: A retrospective clinical study

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (1)

Aim Propofol and opioids are commonly used in anaesthesia, but are highly susceptible to haemodynamic instability, thereby threatening the patient's s......

Safety of off-label dose reduction of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (2)

Aim To investigate the effects of off-label non-vitamin K oral anticoagulant (NOAC) dose reduction compared with on-label standard dosing in atrial fi......

Population pharmacokinetics of nadroparin for thromboprophylaxis in COVID-19 intensive care unit patients

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (5)

AimsNadroparin is administered to COVID-19 intensive care unit (ICU) patients as thromboprophylaxis. Despite existing population pharmacokinetic (PK) ......

Direct-to-participant investigational medicinal product supply in clinical trials in Europe: Exploring the experiences of sponsors, site staff and couriers

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; ()

AimsInsights into the current practice of direct-to-participant (DtP) supply of investigational medicinal product (IMP) in the context of clinical tri......

Different effects of chronic omeprazole use on osteoporotic fractures rate in the elderly

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; ()

Aims: To investigate the potential association of chronic use of omeprazole with the occurrence of osteoporotic fractures (OF) in community-dwelling e......

International pharmacy students' perceptions towards artificial intelligence in medicine-A multinational, multicentre cross-sectional study

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; ()

Aims: To explore international undergraduate pharmacy students' views on integrating artificial intelligence (AI) into pharmacy education and practice......

Development and validation of a predictive tool for adverse drug reactions in neonates under intensive care

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; ()

AimsNeonates hospitalized in neonatal intensive care units (NICUs) commonly experience adverse drug reactions (ADRs). Thus, we aimed to develop and va......

Physiologically based pharmacokinetic and pharmacodynamic modelling of alprazolam: Implications for anxiety and addiction

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (8)

AimsAlprazolam is an anxiolytic compound that can lead to psychological and physiological dependence especially with prolonged use. This study utilize......

A population pharmacokinetic-pharmacodynamic model evaluating efficacy of nalbuphine extended-release in patients with prurigo nodularis

期刊: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (7)

AimsPopulation pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) models were used to describe the exposure-response (E-R) relationship ......

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