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Drug interactions causing warfarin overdose in a patient with a pancreatic cancer : a case report.

期刊: CHEMOTHERAPY, 2023; 68 (2)

Mistletoe, Viscum album, is a medicinal plant used in complementary medicine in oncology. Patients don't necessarily mention to their oncologist this ......

Initial therapeutic approach with pembrolizumab in synchronous multiple cancers, including non-small cell lung cancer highly positive for programmed death-ligand 1 expression

期刊: CHEMOTHERAPY, 2023; 68 (3)

Treatment of synchronous multiple primary cancers is clinically difficult. We report four cases of synchronous primary cancers, including advanced and......

Targeted therapy of non-small cell lung cancer and liver cancer: functional nanocarriers for the delivery of cisplatin and tissue factor pathway inhibitor-2

期刊: CHEMOTHERAPY, 2023; 68 (2)

Introduction: To construct folic acid-modified PEGylated paramagnetic nanoparticles (MNP) co-carrying tissue factor pathway inhibitor-2 (TFPI-2) and c......

Evaluation of a novel combination therapy, based on trifluridine/tipiracil and fruquintinib, against colorectal cancer

期刊: CHEMOTHERAPY, 2023; 68 (2)

Introduction: Trifluridine/tipiracil hydrochloride (FTD/TPI, Lonsurf (R)) is an oral antineoplastic agent that has been approved as a late-stage chemo......

Review Article title: Natural Compounds with Antimicrobial Activities in oral Candida infections during head and neck radiotherapy

期刊: CHEMOTHERAPY, 2023; ()

Backgrounds: Oral colonization and infections are frequently observed in patients during and soon after radiation therapy (RT). Infective mucositis is......

LncRNA BCAR4 promotes oxaliplatin resistance in colorectal cancer by modulating miR-484-3p/RAB5C expression

期刊: CHEMOTHERAPY, 2023; 68 (3)

BackgroundOxaliplatin based chemotherapy resistance is a major cause of recurrence in patients with colorectal cancer (CRC). Increasing evidence indic......

NEW TARGETED DRUGS FOR ACUTE MYELOID LEUKEMIA AND ANTIFUNGALS: PHARMACOKINETIC CHALLENGES AND OPPORTUNITIES

期刊: CHEMOTHERAPY, 2023; 68 (3)

BackgroundAcute myeloid leukemia (AML) is a life-threatening disease whose treatment is made difficult by a number of mutations or receptor overexpres......

Ceramide analogue 5cc overcomes TRAIL-resistance by enhancing JNK activation and repressing XIAP expression in metastatic colon cancer cells

期刊: CHEMOTHERAPY, 2023; 68 (4)

Introduction:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered to be an effective apoptosis inducer due to its selectivity......

Ibrutinib and Bruton's tyrosine kinase inhibitors in chronic lymphocytic leukemia: focus on atrial fibrillation and ventricular tachyarrhythmias/sudden cardiac death

期刊: CHEMOTHERAPY, 2023; 68 (2)

Background: The natural history of chronic lymphocytic leukemia (CLL) was dramatically improved by the introduction of ibrutinib, a Bruton's kinase (B......

Fusidic Acid and Its Major Active Metabolite Penetration into Cerebrospinal Fluid for Assessing Treatment of Intracranial Infections

期刊: CHEMOTHERAPY, 2023; 68 (1)

Fusidic acid (FA) had excellent antimicrobial effects due to its unique mechanism of action. Since 1962, FA has been widely used in the systemic and t......

SARS-CoV-2 infection in patients treated with azacitidine and venetoclax for acute leukemia - a report of a case series treated in a single institution

期刊: CHEMOTHERAPY, 2023; 68 (1)

Introduction Venetoclax combined with azacitidine (AZA-VEN) constitutes an option for the treatment of acute myeloid leukemia. There is however no dat......

Risk of Immune-Related Pneumonitis with PD-1/PD-L1 Inhibitors in Different Cancer Types and Treatment Regimens: A Systematic Review and Meta-Analysis of 22 Randomized Controlled Trials

期刊: CHEMOTHERAPY, 2023; 68 (1)

Background: Pneumonitis, the specific toxicity associated with PD-1/PD-L1 inhibitors, is severe and potentially life threatening, and its incidence an......

Circulating endothelial cell (CEC) kinetic in patients with Multiple Myeloma (MM) who receive Au-HSCT (Autologous Hematopoietic Stem Cell Transplantation)

期刊: CHEMOTHERAPY, 2023; 68 (3)

Introduction: Neoangiogenesis has a crucial role in Multiple Myeloma (MM) and Circulating Endothelial Cells (CECs) contribute to neovascularization by......

FDG-PET in Relapsed/Refractory Hodgkin Lymphoma: a practical approach.

期刊: CHEMOTHERAPY, 2023; ()

Background:Positron emission tomography (PET) with the use of 18F-fluorodeoxyglucose (FDG), implemented with low dosage Computer Tomography (CT), is t......

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