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Construction of a multi-classified decision tree model for identifying malignant pleural effusion and tuberculous pleural effusion

期刊: CLINICAL BIOCHEMISTRY, 2023; 120 ()

Objective: Pleural effusion (PE) is a common clinical complication associated with various disorders. We aimed to utilize laboratory variables and the......

Low partial pressure of oxygen causes significant and unrecognized under-recovery of glucose on blood gas analyzers

期刊: CLINICAL BIOCHEMISTRY, 2023; 111 ()

Background: Blood gas analyzers employing glucose-oxidase biosensors under-recover glucose when pO2 is low. The manufacturer of the GEM (R) PremierTM ......

Retrospective analysis of serum free light chain reference intervals and risk for monoclonal gammopathy suggests different limits than those in international guidelines

期刊: CLINICAL BIOCHEMISTRY, 2023; 118 ()

Objectives: Recent reference interval studies of the serum free light chain (FLC) test using contemporary instruments display divergence with the diag......

Establishment of a reference interval for total carbon dioxide using indirect methods in Chinese populations living in high-altitude areas: A retrospective real-world analysis

期刊: CLINICAL BIOCHEMISTRY, 2023; 119 ()

Background: Hypoxia leads to different concentrations of the bicarbonate buffer system in Tibetan people. Indirect methods were used to establish the ......

Circulating glypican-4 is a new predictor of all-cause mortality in patients with heart failure

期刊: CLINICAL BIOCHEMISTRY, 2023; 121 ()

Background: Heart failure confers a high burden of morbidity and mortality. However, risk prediction in heart failure patients still is limited. Blood......

Towards achieving the end of the HIV epidemic: Advances, challenges and scaling-up strategies

期刊: CLINICAL BIOCHEMISTRY, 2023; 117 ()

We are entering the 5th decade of the HIV epidemic and although there is no cure, critical advances have been made in treatment, prevention and diagno......

Not T too! False elevations in high-sensitivity cardiac troponin T (hs-TnT) following specimen transport

期刊: CLINICAL BIOCHEMISTRY, 2023; 115 ()

Though false elevations attributed to preanalytical specimen handling have been widely reported for Troponin I (TnI), Troponin T (TnT) has appeared mo......

Comparison of reference intervals for biochemical and hematology markers derived by direct and indirect procedures based on the Isfahan cohort study

期刊: CLINICAL BIOCHEMISTRY, 2023; 116 ()

Introduction: Indirect methods for reference interval (RI) establishment apply statistical techniques to generate RIs for test result interpretation u......

Variation in processes and reporting of cerebrospinal fluid oligoclonal banding and associated tests and calculated indices across Canadian clinical laboratories

期刊: CLINICAL BIOCHEMISTRY, 2023; 116 ()

Objectives: Multiple sclerosis is diagnosed based on clinical and laboratory findings, including cerebrospinal fluid (CSF) oligoclonal banding (OCB) a......

Serum matrix metalloproteinase-9 (MMP9) and amyloid-beta protein precursor (APP) as potential biomarkers in children with Fragile-X syndrome: A cross sectional study

期刊: CLINICAL BIOCHEMISTRY, 2023; 122 ()

Introduction: Fragile-X syndrome(FXS) is a neurological disease caused by abnormal repeats in the 5 ' untranslated region of the FMR1 gene leading to ......

Correlation between inflammatory biomarkers, cognitive function and glycemic and lipid profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis

期刊: CLINICAL BIOCHEMISTRY, 2023; 121 ()

This study aimed to quantitatively estimate the correlation between systemic inflammation with cognitive function, as well as glycemic and lipid profi......

A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use

期刊: CLINICAL BIOCHEMISTRY, 2023; 112 ()

Background: Urine drug testing (UDT) monitors prescription compliance and/or drug abuse. However, inter-pretation of UDT results obtained by liquid ch......

Age affects the diagnostic accuracy of serum N-terminal pro-B-type natriuretic peptide for heart failure in patients with pleural effusion

期刊: CLINICAL BIOCHEMISTRY, 2023; 114 ()

Background: Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a well-recognized diagnostic marker for heart failure (HF) in patients with......

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