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KIAA1429 Promotes Nasopharyngeal Carcinoma Progression by Mediating m6A Modification of PTGS2

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (4)

Emerging evidence suggests that dysregulation of a N6-methyladenosine (m6A) methyltransferase KIAA1429 participates in the pathogenesis of multiple ca......

Personalized Precision Immunotherapy for Amyotrophic Lateral Sclerosis (ALS)

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (2)

Neurological syndrome amyotrophic lateral sclerosis (ALS) affects motor neurons and is characterized by progressive motor neuron loss in the brain and......

Study of Therapeutic Mechanisms of Puerarin against Sepsis-Induced Myocardial Injury by Integrating Network Pharmacology, Bioinformatics Analysis, and Experimental Validation

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (3)

Myocardial injury is the most prevalent and serious complication of sepsis. The potential of puerarin (Pue) to treat sepsis-induced myocardial injury ......

Losartan-Induced Angioedema with Acute Hypoxemic Respiratory Failure (Anaphylaxis): A Case Report

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (4)

Angioedema is a condition characterized by swelling of the skin or mucosa resulting from loss of vascular integrity that leads to swelling of mucosal ......

m6A Writer METTL3-Mediated lncRNA LINC01125 Prevents the Malignancy of Papillary Thyroid Cancer

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (3)

Background: Long non-coding RNA (lncRNA) LINC01125 is an anti-tumor factor in a variety of tumors, and regulates cancer cell function. However, its fu......

Recent Advancement and Novel Application of Natural Polyphenols for the Treatment of Allergy Asthma: From Phytochemistry to Biological Implications

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (4)

Allergic diseases, primarily IgE-mediated, exert a substantial global health burden. A pivotal role in allergic reactions is played by mast cells, wit......

Regulation of Cytotoxic Immune Effector Function by AJ3 Probiotic Bacteria in Amyotrophic Lateral Sclerosis (ALS)

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (1)

Our recent studies indicated that amyotrophic lateral sclerosis (ALS) patients suffer from significantly elevated levels of interferon-gamma (IFN-?) s......

Identification of Potential Targets and Mechanisms of Sinomenine in Allergic Rhinitis Treatment Based on Network Pharmacology and Molecular Docking

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (4)

This study aimed to investigate the potential targets and molecular mechanism of sinomenine in treating allergic rhinitis (AR) using network pharmacol......

Interleukin 34 in Disease Progressions: A Comprehensive Review

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (6)

IL-34, a cytokine, discovered a decade before and is known to be a colony stimulating factor CSF-1 receptor (CSF-1R) ligand. Along with CSF-1R, it als......

Network Pharmacology to Reveal the Molecular Mechanisms of Rutaceous Plant-derived Limonin Ameliorating Non-alcoholic Steatohepatitis

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (5)

Background: Limonin shows promise in alleviating non-alcoholic fatty liver disease. We investigated the mechanisms of limonin against non-alcoholic st......

Physical Activity Increases Immunity to COVID-19 Infection

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (5)

Coronavirus are truly one of the maximum critical fantastic-stranded non-segmented RNA viruses, named after the approximately 126-nm-diameter envelope......

Th17 Cells: Orchestrators of Mucosal Inflammation and Potential Therapeutic Targets

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (5)

T helper 17 (Th17) cells represent a specialized subgroup of effector CD4+ T cells known for their role in provoking neutrophil-driven tissue inflamma......

Successes and Challenges in Taming the Beast: Cytotoxic Immune Effectors in Amyotrophic Lateral Sclerosis

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (1)

Amyotrophic lateral sclerosis (ALS) is a neurological disease characterized by the progressive loss of motor neurons in the brain and spinal cord. No ......

ZC3H13 Enhances the Malignancy of Cervical Cancer by Regulating m6A Modification of CKAP2

期刊: CRITICAL REVIEWS IN IMMUNOLOGY, 2023; 43 (6)

Sustained expression of zinc finger CCCH-type containing 13 (ZC3H13) in tumors is essential for cancer cell malignancy; however, our understanding of ......

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