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The Utilization of Plant-Material-Loaded Vesicular Drug Delivery Systems in the Management of Pulmonary Diseases

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (12)

Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constitu......

SRY-Related Transcription Factors in Head and Neck Squamous Cell Carcinomas: In Silico Based Analysis

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (12)

Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer and the fifth cause of cancer-related deaths worldwide with a poor 5-year su......

A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (12)

Lipids are important modifiers of protein function, particularly as parts of lipoproteins, which transport lipophilic substances and mediate cellular ......

Deuterium Content of the Organic Compounds in Food Has an Impact on Tumor Growth in Mice

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (1)

Research with deuterium-depleted water (DDW) in the last two decades proved that the deuterium/hydrogen ratio has a key role in cell cycle regulation ......

Flow Cytometry Detection of Anthracycline-Treated Breast Cancer Cells: An Optimized Protocol

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (1)

The use of anthracycline derivatives was approved for the treatment of a broad spectrum of human tumors (i.e., breast cancer). The need to test these ......

Identification of Dietary Bioflavonoids as Potential Inhibitors against KRAS G12D Mutant-Novel Insights from Computer-Aided Drug Discovery

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (3)

The KRAS G12D mutation is very frequent in many cancers, such as pancreatic, colon and lung, and has remained undruggable for the past three decades, ......

The In Vitro and In Vivo Anticancer Effect of Photomed for Photodynamic Therapy: Comparison with Photofrin and Radachlorin

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (3)

To overcome the limitation of conventional cancer treatments, photodynamic therapy (PDT) has been introduced as another treatment option. PDT provides......

Host-Based Treatments for Severe COVID-19

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (4)

COVID-19 has been a global health problem since 2020. There are different spectrums of manifestation of this disease, ranging from asymptomatic to ext......

Mouse CCL9 Chemokine Acts as Tumor Suppressor in a Murine Model of Colon Cancer

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (4)

Colorectal cancer is the third most frequently diagnosed cancer in the world. Despite extensive studies and apparent progress in modern strategies for......

A Comparative Study on the Carcass and Meat Chemical Composition, and Lipid-Metabolism-Related Gene Expression in Korean Hanwoo and Brindle Chikso Cattle

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (4)

The objective of this study was to elucidate the effect of cattle breed on carcass and meat chemical composition, fatty acid profiles, and lipid-metab......

Synergistic Effects of New Curcumin Analog (PAC) and Cisplatin on Oral Cancer Therapy

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (6)

Oral cancer has traditionally been treated with surgery, radiotherapy, chemotherapy, or a combination of these therapies. Although cisplatin, a chemot......

Characterization of Mammary Tumors Arising from MMTV-PyVT Transgenic Mice

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (6)

Among genetically engineered mouse models of breast cancer, MMTV-PyVT is a mouse strain in which the oncogenic polyoma virus middle T antigen is drive......

Gene Expression Profiles of Methyltransferases and Demethylases Associated with Metastasis, Tumor Invasion, CpG73 Methylation, and HPV Status in Head and Neck Squamous Cell Carcinoma

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (6)

Epigenetic studies on the role of DNA-modifying enzymes in HNSCC tumorigenesis have focused on a single enzyme or a group of enzymes. To acquire a mor......

Targeting RAF Isoforms and Tumor Microenvironments in RAS or BRAF Mutant Colorectal Cancers with SJ-C1044 for Anti-Tumor Activity

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (7)

Colorectal cancer (CRC) is a significant global health issue characterized by a high prevalence of KRAS gene mutations. The RAS/MAPK pathway, involvin......

Axonal Protection by Oral Nicotinamide Riboside Treatment with Upregulated AMPK Phosphorylation in a Rat Glaucomatous Degeneration Model

期刊: CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023; 45 (9)

Nicotinamide riboside (NR), a precursor of nicotinamide adenine dinucleotide (NAD+), has been studied to support human health against metabolic stress......

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