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Responsive Role of Nanomedicine in the Tumor Microenvironment and Cancer Drug Resistance

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (29)

Cancer remains a major worldwide health challenge. Current studies emphasize the tumor microenvironment that plays a vital role in tumor proliferation......

Non-surgical In Vivo Germ Cell-mediated Gene Editing by CRISPR Mutagenic Chain Reaction with the Aid of Magnetic Nanoparticles

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (7)

Gene therapy via germline cells leads to a permanent genetic modification. The promise of this method is due to its potential for providing a stable t......

Aptamer-based Biosensors: Promising Sensing Technology for Diabetes Diagnosis in Biological Fluids

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (30)

Diabetes is a chronic disease state in which the pancreas fails to secrete sufficient insulin, resulting in an elevation of blood glucose levels. As o......

The Regulation Role of Ferroptosis Mechanism of Anti-Cancer Drugs and Noncoding RNAs

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (14)

Ferroptosis is a recently discovered type of cell death caused by the accumulation of iron-dependent lipid peroxides and reactive oxygen species that ......

Cellular Functional, Protective or Damaging Responses Associated with Different Redox Imbalance Intensities: A Comprehensive Review

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (34)

Reactive species (RS) are produced in aerobic and anaerobic cells at different concentrations and exposure times, which may trigger diverse responses ......

Broad-Spectrum Anti-Flavivirus Activity and Chemistry of Compounds Containing Sulfur and Oxygen Chalcogens

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (21)

Sulfur and oxygen containing-compounds are a relevant class of derivatives that is constantly growing due to their wide range of pharmacological activ......

Organoid Models of Heart Diseases: Find a New Channel in Improvements of Cardiac Regenerative Medicine

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (33)

We are experiencing a revolution in regenerative medicine. Recent developments in organoid technology have provided unique opportunities for studying ......

Cobalt Ferrite Nanoparticle's Safety in Biomedical and Agricultural Applications: A Review of Recent Progress

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (15)

Cobalt ferrite nanoparticles (CFN) have drawn attention as a theranostic agent. Unique physicochemical features of CFN and magnetic properties make CF......

The Role of High-density Lipoprotein in Oral and Dental Diseases

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (20)

High-density lipoprotein (HDL) is the smallest and densest of the lipoproteins. Beyond its well-known cardiovascular protective function, it has other......

Aptamer-based Advances in Skin Cancer Research

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (8)

Cancer diseases have been one of the biggest health threats for the last two decades. Approximately 9% of all diagnosed cancers are skin cancers, incl......

Next-generation Sequencing for Surveillance of Antimicrobial Resistance and Pathogenicity in Municipal Wastewater Treatment Plants

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (1)

The World Health Organization (WHO) ranks antimicrobial resistance (AMR) and various pathogens among the top 10 health threats. It is estimated that b......

Therapeutic Potential of Genistein: Preclinical Studies, Clinical Evidence, and Nanotechnology Application

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; 30 (22)

Genistein (4',5,7-trihydroxyisoflavone) is a natural plant-derived phytoestrogen that can be found, for example, in soybean seeds. Genistein is presen......

Protective Effects of Curcumin and its Analogues via the Nrf2 Pathway in Metabolic Syndrome

期刊: CURRENT MEDICINAL CHEMISTRY, 2023; ()

Metabolic Syndrome (MetS) refers to a set of medical conditions including insulin resistance, central obesity, atherogenic dyslipidemia, and hypertens......

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