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Sex and reproductive development impact skin mucosal epithelium immunity, antimicrobial capacity, and up-regulation of immune-related gene of goldfish (Carassius auratus)

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 138 ()

This study evaluated the epidermis mucosal capacity of goldfish (Carassius auratus) during different stages of reproductive development in both female......

Identification of Nrf2/Keap1 pathway and its transcriptional regulation of antioxidant genes after exposure to microcystins in freshwater mussel Cristaria plicata

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 141 ()

Microcystins (MC) are one of the most abundant and widely distributed cyanotoxins in aquatic systems. MC inhibits the functions of protein phosphatase......

Long non-coding RNA LTCONS8875 regulates innate immunity by up-regulating IRAK4 in Miichthys miiuy (miiuy croaker)

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 142 ()

In recent years, many studies have shown that long non-coding RNAs (lncRNAs) can regulate many biochemical processes, such as cell growth, proliferati......

MiR-217 targets TBK1 to modulate inflammatory response in grass carp following infection with Aeromonas hydrophila

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 143 ()

The current study demonstrated that miR-217 modulates inflammation in grass carp (Ctenopharyngodon Idella) infected with Aeromonas hydrophila. Bacteri......

Antiviral immunity of grouper MAP kinase phosphatase 1 to Singapore grouper iridovirus infection

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 143 ()

Singapore grouper iridovirus (SGIV), with various mechanisms for evading and modulating host, has inflicted heavy economic losses in the grouper aquac......

Functional of tongue sole (Cynoglossus semilaevis) gamma-interferon-inducible lysosomal thiol reductase with implications in innate immune reponse depend on CXXC active site

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 147 ()

The enzyme gamma-interferon-inducible lysosomal thiol reductase (GILT) plays an important role in promoting the processing and presentation of major h......

IRF9 inhibits CyHV-3 replication by regulating the PI3K-AKT signalling pathway in common carp (Cyprinus carpio) epithelial cells

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 148 ()

Interferon regulatory factor 9 (IRF9) is an important transcriptional regulator involved in innate and adaptive immunity. Cyprinid herpesvirus-3 (CyHV......

Chicken miR-26a-5p modulates MDA5 during highly pathogenic avian influenza virus infection

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 149 ()

MicroRNAs play crucial roles in immune-related pathways in host animals. In this study, we aimed to investigate the systemic biological function of gg......

Perforin and granzyme A release as novel tool to measure NK cell activation in chickens

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 149 ()

Natural killer (NK) cells are cytotoxic lymphocytes that are present in the circulation but also in many organs including spleen and gut, where they p......

BdcSP10 is a prophenoloxidase-activating protease in Bactrocera dorsalis

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 138 ()

Insects rely on a powerful and efficient innate immune system against microbial invaders. One of the most important immune processes is the melanizati......

Extracellular vesicles of Clonorchis sinensis promote IL-6 and TNF-α secretion via the Toll-like receptor 9-mediated ERK pathway in biliary epithelial cells

期刊: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023; 139 ()

Clonorchis sinensis is closely associated with cholangitis, cholecystitis, biliary fibrosis and cholangiocarcinoma. The present study elucidated the r......

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