期刊: EMBO JOURNAL, 2023; 42 (9)
Cellular condensates can comprise membrane-less ribonucleoprotein assemblies with liquid-like properties. These cellular condensates influence various......
期刊: EMBO JOURNAL, 2023; 42 (9)
Human in vitro oogenesis provides a framework for clarifying the mechanism of human oogenesis. To create its benchmark, it is vital to promote in vitr......
期刊: EMBO JOURNAL, 2023; 42 (9)
The accumulation of senescent cells is recognised as a driver of tissue and organismal ageing. One of the gold-standard hallmarks of a senescent cell ......
期刊: EMBO JOURNAL, 2023; 42 (10)
Epithelial cells acquire mesenchymal phenotypes through epithelial-mesenchymal transition (EMT) during cancer progression. However, how epithelial cel......
期刊: EMBO JOURNAL, 2023; 42 (16)
Meiotic recombination is initiated by the formation of DNA double-strand breaks (DSBs), essential for fertility and genetic diversity. In the mouse, D......
期刊: EMBO JOURNAL, 2023; 42 (20)
Mitochondrial DNA (mtDNA) leakage into the cytoplasm can occur when cells are exposed to noxious stimuli. Specific sensors recognize cytoplasmic mtDNA......
期刊: EMBO JOURNAL, 2023; 42 (23)
Primary Sj & ouml;gren's syndrome (pSS) is an inflammatory autoimmune disorder largely mediated by type I and II interferon (IFN). The potential c......
期刊: EMBO JOURNAL, 2023; 42 (3)
The widely occurring bacterial RNA chaperone Hfq is a key factor in the post-transcriptional control of hundreds of genes in Pseudomonas aeruginosa. H......
期刊: EMBO JOURNAL, 2023; 42 (11)
Many cellular functions are carried out by protein pairs or families, providing robustness alongside functional diversity. For such processes, it rema......
期刊: EMBO JOURNAL, 2023; 42 (12)
Translation initiates when the eIF4F complex binds the 5 ' mRNA cap, followed by 5 ' untranslated region scanning for the start codon by scanning ribo......
期刊: EMBO JOURNAL, 2023; 42 (14)
The mature mammalian brain connectome emerges during development via the extension and pruning of neuronal connections. Glial cells have been identifi......
期刊: EMBO JOURNAL, 2023; 42 (14)
Interferons (IFNs) are antiviral cytokines that play a key role in the innate immune response to viral infections. In response to viral stimuli, cells......
期刊: EMBO JOURNAL, 2023; 42 (16)
CDC14, originally identified as crucial mediator of mitotic exit in budding yeast, belongs to the family of dual-specificity phosphatases (DUSPs) that......
Sequences that form DNA secondary structures, such as G-quadruplexes (G4s) and intercalated-Motifs (iMs), are abundant in the human genome and play va......
期刊: EMBO JOURNAL, 2023; 42 (23)
The main goals and challenges for the life science communities in the Open Science framework are to increase reuse and sustainability of data resource......