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Osteogenesis Imperfecta: Mechanisms and Signaling Pathways Connecting Classical and Rare OI Types

期刊: ENDOCRINE REVIEWS, 2022; 43 (1)

Osteogenesis imperfecta (OI) is a phenotypically and genetically heterogeneous skeletal dysplasia characterized by bone fragility, growth deficiency, ......

JIF:17.27

Fat Cell Size: Measurement Methods, Pathophysiological Origins, and Relationships With Metabolic Dysregulations

期刊: ENDOCRINE REVIEWS, 2022; 43 (1)

The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes, cardiovascular diseases and many other chronic diseases. Fat ce......

JIF:17.27

Personalized Management of Pheochromocytoma and Paraganglioma

期刊: ENDOCRINE REVIEWS, 2022; 43 (2)

Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape that allows their assignment to clusters based on underlying geneti......

JIF:17.27

Optimal Thyroid Hormone Replacement

期刊: ENDOCRINE REVIEWS, 2022; 43 (2)

Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed. Despite the basic tenets of initiating and adjusting levothyrox......

JIF:17.27

Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement

期刊: ENDOCRINE REVIEWS, 2022; 43 (3)

During the last decade, there has been great interest in elucidating the biological role of extracellular vesicles (EVs), particularly, their hormone-......

JIF:17.27

Secondary Osteoporosis

期刊: ENDOCRINE REVIEWS, 2022; 43 (2)

Osteoporosis is a global public health problem, with fractures contributing to significant morbidity and mortality. Although postmenopausal osteoporos......

JIF:17.27

Myostatin/Activin Receptor Ligands in Muscle and the Development Status of Attenuating Drugs

期刊: ENDOCRINE REVIEWS, 2022; 43 (2)

Muscle wasting disease indications are among the most debilitating and often deadly noncommunicable disease states. As a comorbidity, muscle wasting i......

JIF:17.27

Stem Cells and Organs-on-chips: New Promising Technologies for Human Infertility Treatment

期刊: ENDOCRINE REVIEWS, 2022; 43 (5)

Having biological children remains an unattainable dream for most couples with reproductive failure or gonadal dysgenesis. The combination of stem cel......

JIF:17.27

Update on Biology and Genomics of Adrenocortical Carcinomas: Rationale for Emerging Therapies

期刊: ENDOCRINE REVIEWS, 2022; 43 (6)

The adrenal glands are paired endocrine organs that produce steroid hormones and catecholamines required for life. Adrenocortical carcinoma (ACC) is a......

JIF:17.27

A Modern Approach to Dyslipidemia

期刊: ENDOCRINE REVIEWS, 2022; 43 (4)

Lipid disorders involving derangements in serum cholesterol, triglycerides, or both are commonly encountered in clinical practice and often have impli......

JIF:17.27

Deconstructing a Syndrome: Genomic Insights Into PCOS Causal Mechanisms and Classification

期刊: ENDOCRINE REVIEWS, 2022; 43 (6)

Polycystic ovary syndrome (PCOS) is among the most common disorders in women of reproductive age, affecting up to 15% worldwide, depending on the diag......

JIF:17.27

Congenital Adrenal Hyperplasia-Current Insights in Pathophysiology, Diagnostics, and Management

期刊: ENDOCRINE REVIEWS, 2022; 43 (1)

Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting cortisol biosynthesis. Reduced activity of an enzyme requir......

JIF:17.27

From Molecule to Behavior: Hypocretin/orexin Revisited From a Sex-dependent Perspective

期刊: ENDOCRINE REVIEWS, 2022; 43 (4)

The hypocretin/orexin (Hcrt/Orx) system in the perifornical lateral hypothalamus has been recognized as a critical node in a complex network of neuron......

JIF:17.27

Post-translational Modifications: The Signals at the Intersection of Exercise, Glucose Uptake, and Insulin Sensitivity

期刊: ENDOCRINE REVIEWS, 2022; 43 (4)

Diabetes is a global epidemic, of which type 2 diabetes makes up the majority of cases. Nonetheless, for some individuals, type 2 diabetes is eminentl......

JIF:17.27

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