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Dual role of glycans and binding receptors in pathogenesis of enveloped viruses (by mainly focusing on two recent pandemics)

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

A period of about a decade has been estimated to pass for the emergence of a new infectious strain of a virus that may lead to the occurrence of a pan......

Helicobacter pylori virulence factors: subversion of host immune system and development of various clinical outcomes

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Helicobacter pylori (H. pylori) is a worldwide spread bacterium, co-evolving with humans for at least 100 000 years. Despite the uncertainty about the......

Molecular mechanisms of action of negative pressure wound therapy: a systematic review

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Negative pressure wound therapy (NPWT) has significantly advanced wound care and continues to find new applications. Its effects at a molecular level ......

Targeting N-cadherin (CDH2) and the malignant bone marrow microenvironment in acute leukaemia

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

This review discusses current research on acute paediatric leukaemia, the leukaemic bone marrow (BM) microenvironment and recently discovered therapeu......

Telomerase inhibition in malignant gliomas: a systematic review

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Glioblastoma (GBM) is the most frequent adult malignant brain tumour and despite different therapeutic efforts, the median overall survival still rang......

A systematic review on antimicrobial activities of green synthesised Selaginella silver nanoparticles

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Background. Metallic nanoparticles from different natural sources exhibit superior therapeutic options as compared to the conventional methods. Selagi......

Dysregulated phosphate metabolism in autism spectrum disorder: associations and insights for future research

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Studies of autism spectrum disorder (ASD) related to exposure to toxic levels of dietary phosphate are lacking. Phosphate toxicity from dysregulated p......

Inflammasomes in breast cancer: the ignition spark of progression and resistance?

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Inflammation and immune evasion are major key players in breast cancer (BC) progression. Recently, the FDA approved the use of anti-programmed death-l......

Toxicology of pharmaceutical and nutritional longevity compounds

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Aging is the most prominent risk factor for many diseases, which is considered to be a complicated biological process. The rate of aging depends on th......

MicroRNAs in cancer metastasis: biological and therapeutic implications

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Cancer metastasis is the primary cause of cancer-related deaths. The seeding of primary tumours at a secondary site is a highly inefficient process re......

Fusobacterium nucleatum: a novel immune modulator in breast cancer?

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Breast cancer was the most commonly diagnosed cancer worldwide in 2020. Greater understanding of the factors which promote tumour progression, metasta......

Identity matters: cancer stem cells and tumour plasticity in head and neck squamous cell carcinoma

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

Head and neck squamous cell carcinoma (HNSCC) represents frequent yet aggressive tumours that encompass complex ecosystems of stromal and neoplastic c......

New perspective on DNA response pathway (DDR) in glioblastoma, focus on classic biomarkers and emerging roles of ncRNAs

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

BackgroundGlioblastoma (GBM) is the most frequent type of primary brain cancer, having a median survival of only 15 months. The current standard of ca......

Evaluation of prostate cancer tissue metabolomics: would clinics utilise it for diagnosis?

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

The difficulty of diagnosing prostate cancer (PC) with the available biomarkers frequently leads to over-diagnosis and overtreatment of PC, underscori......

Autophagic mechanisms in longevity intervention: role of natural active compounds

期刊: EXPERT REVIEWS IN MOLECULAR MEDICINE, 2023; 25 ()

The term 'autophagy' literally translates to 'self-eating' and alterations to autophagy have been identified as one of the several molecular changes t......

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