筛选条件 共查询到441条结果
排序方式
An updated patent review of Nrf2 activators (2020-present)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (1)

IntroductionThe nuclear factor erythroid 2-related factor 2 (Nrf2) is a pivotal transcription factor that controls the expression of numerous cytoprot......

Conjugates of monocyclic β-lactams and siderophore mimetics: a patent evaluation (WO2023023393)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; ()

Introduction: beta-Lactams, which include monobactams, remain the most important class of antibiotics worldwide. Aztreonam, the only monobactam in cli......

An updated patent review of matrix metalloproteinase (MMP) inhibitors (2021-present)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (10)

IntroductionMatrix metalloproteinases (MMPs) are strongly interlinked with the progression and mechanisms of several life-threatening diseases includi......

Drugs and nanoformulations for the management of Leishmania infection: a patent and literature review (2015-2022)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (3)

Introduction: Leishmaniasis is an important disease caused by parasites of the Leishmania. Due to the urgent need for financial incentives and researc......

Therapeutic applications of thymosin peptides: a patent landscape 2018-present

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (12)

Introduction: Thymosins are small proteins found mainly in the thymus. They are involved in several biological processes, including immunoregulation, ......

Therapeutic applications of thymosin peptides: a patent landscape 2018-present

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; ()

Introduction: Thymosins are small proteins found mainly in the thymus. They are involved in several biological processes, including immunoregulation, ......

A patent review of selective CDK9 inhibitors in treating cancer

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (4)

IntroductionThe dysregulation of CDK9 protein is greatly related to the proliferation and differentiation of various cancers due to its key role in th......

A patent review of EZH2 inhibitors from 2017 and beyond

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (4)

IntroductionEZH2 is an important epigenetic regulator that forms the PRC2 complex with SUZ12, EED and RbAp46/48. As the key catalytic subunit of PRC2,......

Pitfalls in patenting academic CAR-T cells therapy

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (5)

IntroductionEmerging immunotherapies are pushing the boundaries of cancer treatment, with chimeric antigen receptor (CAR)-T cell therapy being one of ......

The next generation of EGFR inhibitors: a patenting perspective of PROTACs based EGFR degraders

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; ()

Introduction: Abnormal expression of epidermal growth factor receptor (EGFR) contributes to tumor development, especially in non-small cell lung cance......

Are patents important indicators of innovation for Chagas disease treatment?

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (3)

IntroductionChagas disease is a neglected, endemic disease in 21 countries, spreading to non-endemic countries too. Like other neglected diseases affe......

An updated patent review of anaplastic lymphoma kinase inhibitors (2018-2022)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (4)

IntroductionAnaplastic lymphoma kinase (ALK), a receptor tyrosine kinase in the insulin receptor superfamily, has emerged as a promising drug target f......

Patent landscape highlighting therapeutic implications of peptides targeting myristoylated alanine-rich protein kinase-C substrate (MARCKS)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (6)

IntroductionMARCKS protein, a protein kinase C (PKC) substrate, is known to be at the intersection of several intracellular signaling pathways and pla......

A patent review of MAPK inhibitors (2018-present)

期刊: EXPERT OPINION ON THERAPEUTIC PATENTS, 2023; 33 (6)

IntroductionThe mitogen-activated protein kinase (MAPK) family consist of p38 MAP kinases, c-Jun N-terminal kinases (JNKs) and extracellular signal-re......

共441条页码: 1/30页15条/页