期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (7)
IntroductionMultiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative condition affecting the central nervous system (CN......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (9)
IntroductionThe ubiquitin system is an evolutionarily conserved and universal means of protein modification that regulates many essential cellular pro......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (12)
AimsDespite the promise of immunotherapy for gastric adenocarcinoma, resistance is common, necessitating the validation of new targets. Based on our p......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (1)
Introduction: Inflammatory bowel diseases (IBDs) are debilitating chronic inflammatory disorders with increasing prevalence worldwide. Epigenetic regu......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (8)
IntroductionEpilepsies are disorders of neuronal excitability characterized by spontaneously recurrent focal and generalized seizures, some of which r......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (3)
IntroductionSpinal cord injury (SCI) affects 25,000-50,000 people around the world each year and there is no cure for SCI patients currently. The prim......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (4-5)
IntroductionTau has commanded much attention as a potential therapeutic target in neurodegenerative diseases. Tau pathology is a hallmark of primary t......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (12)
IntroductionThe extensive heterogeneity of prostate cancer (PCa) and multilayered complexity of progression to castration-resistant prostate cancer (C......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (8)
IntroductionDespite encouraging advances in radiation and surgical treatment, chordomas remain resistant to chemotherapy and local recurrence is commo......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (1)
IntroductionAsthma is characterized by enhanced airway contractility and remodeling where airway smooth muscle (ASM) plays a key role, modulated by in......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; ()
Introduction: The growth of antibiotic resistance among bacterial pathogens is an impending global threat that can only be averted through the develop......
期刊: EXPERT OPINION ON THERAPEUTIC TARGETS, 2023; 27 (12)
IntroductionIn medicinal chemistry, privileged structures have been frequently exploited as a successful template for drug discovery. Common simple sc......