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THROMBOSIS IN PATIENTS WITH HEREDITARY FIBRINOGEN DEFICIENCY

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (2)

Introduction. In most cases, in patients with hereditary fibrinogen deficiency, clinical manifestations are represented by bleeding of varying intensi......

JIF:0.284

MECHANISMS OF ACTION OF IMMUNOMODULATORY DRUGS - FROM TERATOGENICITY TO TREATMENT OF MULTIPLE MYELOMA

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (2)

Introduction. Immunomodulatory drugs (IMiDs) are a class of chemical derivatives of thalidomide with numerous immunomodulatory, antiangiogenic, anti-i......

JIF:0.284

STUDY OF THE JANUS KINASE 2 (JAK2) GENE HAPLOTYPE 46/1 ASSOCIATION WITH DRIVER MUTATIONS OF CHRONIC Ph-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (3)

Introduction. Haplotype JAK2 46/1 is associated with more frequent development of Ph-negative myeloproliferative neoplasms (MPN) and with an increased......

JIF:0.284

INTENSIVE CARE OF LIFE-THREATENING COMPLICATIONS IN ALLOGENEIC HEMATOPOIETIC STEM CELL RECIPIENTS

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (3)

Introduction. Life-threatening complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT) can have a significant influence on the......

JIF:0.284

SUCCESSFUL DIAGNOSIS AND TREATMENT OF FUSARIOSIS IN PATIENT WITH ACUTE LEUKEMIA

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (1)

Introduction. The development of febrile neutropenia complicates the course of the post-chemotherapeutic period in many patients with acute leukemia. ......

JIF:0.284

ROLE OF THE INTENSIVE CARE IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (2)

Introduction. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often complicated by life-threatening conditions. Aim - an analysis of......

JIF:0.284

CONFORMATIONAL DISORDERS OF RBC MEMBRANES DURING LONG-TERM STORAGE

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (2)

Introduction. Packed red blood cells (pRBCs) are the most required component of blood used for transfusion. Storage of erythrocytes in blood bank cond......

JIF:0.284

MEASURES OF SOCIAL SUPPORT FOR BLOOD DONORS DURING THE FORMATION OF THE DONOR MOVEMENT IN THE USSR

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (2)

Introduction. The period of formation of the donor community in the USSR fell on the 30-40s of the twentieth century. The first measures to organize t......

JIF:0.284

ANALYSIS OF THE EFFECTIVENESS OF THE SIRS, qSOFA AND MEWS SCALE FOR THE SEPSIS IDENTIFICATION IN ONCOHEMATOLOGICAL PATIENTS

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (3)

Introduction. Sepsis is one of the main causes of high mortality in oncohematological patients. Sepsis is diagnosed using different scoring scales, bu......

JIF:0.284

INFECTIOUS COMPLICATIONS AND THEIR CONTRIBUTING RISK FACTORS AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (1)

Introduction. Infections are among the most common complications after allogeneic hematopoietic stem cell transplantation. Aim - to provide a literatu......

JIF:0.284

INTERIM RESULTS OF THE PML-16, PML-19 PROTOCOLS FOR PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA THERAPY

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (3)

Introduction. Primary mediastinal lymphoma (PML) is an aggressive lymphoid tumor treatment success of which is determined by induction therapy. To dat......

JIF:0.284

METHODOLOGICAL ASPECTS OF THE DETECTION OF MINIMAL RESIDUAL DISEASE IN PATIENTS WITH ACUTE LEUKEMIA

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (1)

Introduction. The study of minimal residual disease (MRD) has become an integral part of various treatment protocols for acute leukemia. Methods of po......

JIF:0.284

EFFECT OF LOW CONCENTRATION OF MELATONIN ON THE QUALITY OF STORED RED BLOOD CELLS IN VITRO

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (1)

Introduction. Oxidative stress is one of the important causes of red blood cells (RBCs) storage lesion. As a hormone, melatonin (MT) is also an effect......

JIF:0.284

CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY IN ADULT PATIENTS WITH B-CELL LYMPHOPROLIFERATIVE DISEASES

期刊: GEMATOLOGIYA I TRANSFUZIOLOGIYA, 2022; 67 (1)

Introduction. The introduction of chimeric antigen receptor (CAR) T-cell therapy is a promising treatment of patients with relapsed or refractory (R/R......

JIF:0.284

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