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Growth hormone modulates Trypanosoma cruzi infection in vitro

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 64 ()

Objective: Chagas disease (CD) is caused by the protozoan parasite, Trypanosoma cruzi. It affects 7 to 8 million people worldwide and leads to approxi......

JIF:1.832

Expression of IGF-1 receptor and GH receptor in hepatic tissue of patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 65 ()

Objective: The GH and IGF-1 axis is a candidate disease-modifying target in nonalcoholic fatty liver disease (NAFLD) given its lipolytic, anti-inflamm......

JIF:1.832

Dental arches in inherited severe isolated growth hormone deficiency

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 62 ()

Objectives: The growth of the dental arches depends on GH and insulin-like growth factor type 1 (IGF1), but the consequences of GH deficiency (GHD) on......

JIF:1.832

Meta-analysis of MspI derived variants of growth hormone gene associated with milk yield in dairy cattle

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 63 ()

Objective: The present work aimed to obtain common effect sizes for the gene frequency and association of MspI derived variants of growth hormone (GH)......

JIF:1.832

Effect of long-acting growth hormone treatment on endogenous growth hormone secretion in prepubertal patients with idiopathic short stature: A preliminary study

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 66 ()

Long-acting growth hormone (LAGH) is emerging to be a new preparation for treatment of short stature. We aimed to determine whether 12-month treatment......

JIF:1.832

In missed abortion the decrease of IGF-1 down-regulates PI3K/AKT signaling pathway reducing the secretion of progesterone and ?-hCG

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 65 ()

Objective: To explore whether the reduction of IGF-1 in missed abortion down-regulates PI3K/AKT signaling pathway, thereby causing trophoblast cell ap......

JIF:1.832

The role of growth hormone for fertility in women with hypopituitarism

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 63 ()

Growth hormone (GH) is an important regulator of the female reproductive system. In vitro and non-human in vivo studies demonstrate a role of GH in st......

JIF:1.832

The true story of the strong and gentle Acciano's Giant

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 63 ()

This is the story of a giant who lived in Abruzzo 200 years ago. He became a symbol for his people and a strong resilience generator. Gigantism, in th......

JIF:1.832

Reduced exercise-induced growth hormone secretion among children with attention-deficit hyperactivity disorder

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 65 ()

Purpose: Attention-deficit/hyperactivity disorder (ADHD) is typically a chronic, often lifelong condition. Data suggest that ADHD itself and its treat......

JIF:1.832

Subclinical atherosclerosis in acromegaly: Possible association with cardiovascular risk factors rather than disease activity

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 62 ()

Objective: Cardiovascular (CV) disease is still a major cause of excessive morbidity and mortality in patients with active acromegaly, which may be at......

JIF:1.832

Pharmacokinetics and pharmacodynamics of once-weekly administration of JR-142, a long-acting albumin-fused human growth hormone: A rondemized, placebo-controlled phase 1 study

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 67 ()

Objective: Under clinical development for patients with growth hormone deficiency, JR-142 is a long-acting growth hormone with a half-life extended by......

JIF:1.832

Increase of serum lipoprotein (a), an adverse effect of growth hormone treatment

期刊: GROWTH HORMONE & IGF RESEARCH, 2022; 67 ()

A number of reports show that high endogenous, or therapeutic administration of human growth hormone (hGH) cause an increase of serum lipoprotein a, L......

JIF:1.832

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