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Metabolic reprogramming of macrophages instigates CCL21-induced arthritis

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (2)

This study was designed to delineate the functional significance of CCL21 in metabolic reprogramming in experimental arthritis and differentiated rheu......

JIF:4.142

Training the next generation of Sudanese immunologists: a case for mentorship

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (9)

Lack of well-trained Sudanese immunologists hampers the ability of next generation of Sudanese students to get quality immunology training. By narrati......

JIF:4.142

Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (5)

A population of neutrophils recruited into cystic fibrosis (CF) airways is associated with proteolytic lung damage, exhibiting high expression of prim......

JIF:4.142

CD4(+) CAR T cells persist long-term CD4(+) chimeric antigen receptor T cells in for the long journey

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (5)

In a recently published article, Melenhorst et al. performed a longitudinal analysis on chimeric antigen receptor (CAR) T cells isolated from patients......

JIF:4.142

A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (9)

Clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) is an efficient tool for establishing genetic mode......

JIF:4.142

Differentiation of human macrophages with anaphylatoxin C3a impairs alternative M2 polarization and decreases lipopolysaccharide-induced cytokine secretion

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (3)

Anaphylatoxin C3a is a small signaling polypeptide that is generated during complement activation. C3a is involved in the regulation of various innate......

JIF:4.142

Peripheral B-cell dysregulation is associated with relapse after long-term quiescence in patients with multiple sclerosis

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (6)

B cells play a major role in multiple sclerosis (MS), with many successful therapeutics capable of removing them from circulation. One such therapy, a......

JIF:4.142

The ICOS-ICOSL pathway tunes thymic selection

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (3)

Negative selection of developing T cells plays a significant role in T-cell tolerance to self-antigen. This process relies on thymic antigen-presentin......

JIF:4.142

beta-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (4)

Recent advances in the field of host immunity against parasitic nematodes have revealed the importance of macrophages in trapping tissue migratory lar......

JIF:4.142

OCA-B does not act as a transcriptional coactivator in T cells

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (5)

Pou2af1 encodes for OCA-B, a coactivator of OCT-1/2 transcription factors, which plays a key role in B-cell maturation. The function of OCA-B has also......

JIF:4.142

Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (7)

To control infections phagocytes can directly kill invading microbes. Macrophage-expressed gene 1 (Mpeg1), a pore-forming protein sometimes known as p......

JIF:4.142

Immunoglobulin genes, reproductive isolation and vertebrate speciation

期刊: IMMUNOLOGY AND CELL BIOLOGY, 2022; 100 (7)

Reproductive isolation drives the formation of new species, and many genes contribute to this through Dobzhansky-Muller incompatibilities (DMIs). Thes......

JIF:4.142

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