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Transcriptional regulation of human odontogenic ameloblast-associated protein gene by tumor necrosis factor-alpha

期刊: INFLAMMATION RESEARCH, 2022; 71 (1)

Objective Odontogenic ameloblast-associated protein (ODAM) is produced by maturation stage ameloblasts and junctional epithelium (JE). The function of......

JIF:4.114

Internalization of benzylisoquinoline alkaloids by resting and activated bone marrow-derived mast cells utilizes energy-dependent mechanisms

期刊: INFLAMMATION RESEARCH, 2022; 71 (3)

Objective and design Drug delivery to inflammatory cells is dependent upon poorly understood, complex endocytic processes. Berberine (BBR), a benzylis......

JIF:4.114

Inhibition of PRMT6 reduces neomycin-induced inner ear hair cell injury through the restraint of FoxG1 arginine methylation

期刊: INFLAMMATION RESEARCH, 2022; 71 (3)

Objective Hair cells in the inner ear have been demonstrated to be sensitive to the ototoxicity from some beneficial pharmaceutical drugs. This study ......

JIF:4.114

Pregnancy tailors endotoxin-induced monocyte and neutrophil responses in the maternal circulation

期刊: INFLAMMATION RESEARCH, 2022; 71 (5-6)

Objective To comprehensively characterize monocyte and neutrophil responses to E. coli and its product [lipopolysaccharide (LPS) or endotoxin] in vitr......

JIF:4.114

CD14 signaling mediates lung immunopathology and mice mortality induced by Achromobacter xylosoxidans

期刊: INFLAMMATION RESEARCH, 2022; 71 (12)

Objective and design Our research aimed to investigate the role of CD14 in pulmonary infection by Achromobacter xylosoxidans in an experimental murine......

JIF:4.114

Metabolic and inflammatory health in SARS-CoV-2 and the potential role for habitual exercise in reducing disease severity

期刊: INFLAMMATION RESEARCH, 2022; 71 (1)

Introduction The rapid emergence and spread of SARS-CoV-2 in late 2019 has infected millions of people worldwide with significant morbidity and mortal......

JIF:4.114

Splenic T lymphocytes induce the formation of immunosuppressive neutrophils through IFN-gamma in sepsis

期刊: INFLAMMATION RESEARCH, 2022; 71 (1)

Background Despite many advances in treatment, the prognosis of patients with sepsis still remains poor. Polymorphonuclear leukocytes (PMNs) are the f......

JIF:4.114

Trimetazidine affects pyroptosis by targeting GSDMD in myocardial ischemia/reperfusion injury

期刊: INFLAMMATION RESEARCH, 2022; 71 (2)

Objective Trimetazidine (TMZ) exerts a strong inhibitory effect on ischemia/reperfusion (I/R) injury. Inflammation plays a key role in I/R injury. We ......

JIF:4.114

Deciphering the TLR transcriptome and downstream signaling pathway in cerebrospinal fluid in pediatric meningitis

期刊: INFLAMMATION RESEARCH, 2022; 71 (4)

Objective/design Pediatric meningitis is characterized by a colossal inflammatory response to the pathogen in the central nervous system (CNS). This u......

JIF:4.114

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice

期刊: INFLAMMATION RESEARCH, 2022; 71 (10-11)

Background and objective Acute lung injury (ALI)/ acute respiratory distress syndrome (ARDS) was increasingly recognized as one of the most severe acu......

JIF:4.114

Neutrophils as emerging protagonists and targets in chronic inflammatory diseases

期刊: INFLAMMATION RESEARCH, 2022; 71 (12)

Introduction Neutrophils are the key cells of our innate immune system with a primary role in host defense. They rapidly arrive at the site of infecti......

JIF:4.114

C/EBP beta enhances immunosuppression activity of myeloid-derived suppressor cells by a P300-mediated acetylation modification

期刊: INFLAMMATION RESEARCH, 2022; 71 (12)

Objective Myeloid-derived suppressor cells (MDSCs) are a major immunosuppressive population in the tumor microenvironment,inhibiting anti-tumor immune......

JIF:4.114

MiR-21 participates in LPS-induced myocardial injury by targeting Bcl-2 and CDK6

期刊: INFLAMMATION RESEARCH, 2022; 71 (2)

Objective This study aimed to investigate the relationship between miR-21 and lipopolysaccharide (LPS)-induced myocardial injury and its molecular and......

JIF:4.114

COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines

期刊: INFLAMMATION RESEARCH, 2022; 71 (4)

Background The mayhem COVID-19 that was ushered by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) was declared pandemic by the World ......

JIF:4.114

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