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The Impact of Posttraumatic Stress Disorder on Pharmacologic Intervention Outcomes for Adults With Bipolar Disorder: A Systematic Review

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (1)

Background The prevalence of posttraumatic stress disorder (PTSD) co-occurring in people with bipolar disorder (BD) is high. People with BD and PTSD m......

BTRX-246040 Acts Through the Ventrolateral Periaqueductal Gray to Exert Antidepressant-Relevant Actions in Mice

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (7)

Background BTRX-246040, a nociceptin/orphanin FQ peptide receptor antagonist, is being developed for the treatment of depressive patients. However, th......

Effect of MAOA DNA Methylation on Human in Vivo Protein Expression Measured by [11C]harmine Positron Emission Tomography

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (2)

Background: Epigenetic modifications like DNA methylation are understood as an intermediary between environmental factors and neurobiology. Cerebral m......

Activation of the Mu-Delta Opioid Receptor Heteromers Blocks Morphine Rewarding Effects

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (7)

Background Evidence has accumulated demonstrating the existence of opioid receptor heteromers, and recent data suggest that targeting these heteromers......

The Atypical Dopamine Transporter Inhibitor CE-158 Enhances Dopamine Neurotransmission in the Prefrontal Cortex of Male Rats: A Behavioral, Electrophysiological, and Microdialysis Study

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (11)

Background: Dopamine plays a key role in several physiological functions such as motor control, learning and memory, and motivation and reward. The at......

Elucidating the Mechanisms of Sodium Benzoate in Alzheimer Disease: Insights from Quantitative Proteomics Analysis of Serum Samples

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (12)

Background N-methyl-D-aspartate receptors (NMDARs) are crucial components of brain function involved in memory and neurotransmission. Sodium benzoate ......

Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (2)

Background Lysergic acid diethylamide (LSD) is currently being investigated in psychedelic-assisted therapy. LSD has a long duration of acute action o......

PARP1 and OGG1 in Medicated Patients With Depression and the Response to ECT

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (2)

Background Oxidative stress and oxidation-induced DNA damage may contribute to the pathophysiology of depression. Two key mediators of base excision r......

Rolipram Ameliorates Memory Deficits and Depression-Like Behavior in APP/PS1/tau Triple Transgenic Mice: Involvement of Neuroinflammation and Apoptosis via cAMP Signaling

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (9)

Background Alzheimer disease (AD) and depression often cooccur, and inhibition of phosphodiesterase-4 (PDE4) has been shown to ameliorate neurodegener......

Distinct Situational Cue Processing in Individuals with Kleptomania: A Preliminary Study

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (5)

Background Impulse control disorder has been suggested to meet the criteria of addiction and is often considered a behavioral addiction; however, few ......

Spectral Changes of EEG Following a 6-Week Low-Dose Oral Ketamine Treatment in Adults With Major Depressive Disorder and Chronic Suicidality

期刊: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2023; 26 (4)

Background Ketamine has considerable therapeutic potential in alleviating major depressive disorder and chronic suicidality. However, the clinical dia......

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