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Post-radiation treatment of 3,3′-diselenodipropionic acid augments cell kill by modulating DNA repair and cell migration pathways in A549 cells

期刊: IUBMB LIFE, 2023; 75 (10)

Aim of the present study was to test whether ionizing radiation (IR) treatment along with 3,3'-diselenodipropionic acid (DSePA), a redox active organo......

Addressing the impact of high glucose microenvironment on the immunosuppressive characteristics of human mesenchymal stem cells

期刊: IUBMB LIFE, 2023; ()

Mesenchymal stem cells (MSCs) are a therapeutically efficient type of stem cells validated by their ability to treat many inflammatory and chronic con......

Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS-COV-2 targeting main protease and papain-like protease

期刊: IUBMB LIFE, 2023; ()

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be over, but its variants......

The role of the proteasome in mitochondrial protein quality control

期刊: IUBMB LIFE, 2023; 75 (10)

The abundance of each cellular protein is dynamically adjusted to the prevailing metabolic and stress conditions by modulation of their synthesis and ......

Comparative analysis of the potential of the secretomes of cardiac resident stromal cells and fibroblasts

期刊: IUBMB LIFE, 2023; 75 (3)

The secretome of different cell types has been applied on in vitro and in vivo assays, indicating considerable therapeutic potential. However, the cho......

Viral infection and host immune response in diabetes

期刊: IUBMB LIFE, 2023; ()

Diabetes, a chronic metabolic disorder disrupting blood sugar regulation, has emerged as a prominent silent pandemic. Uncontrolled diabetes predispose......

Isolation of fucoxanthin chlorophyll protein complexes of the centric diatom Thalassiosira pseudonana associated with the xanthophyll cycle enzyme diadinoxanthin de-epoxidase

期刊: IUBMB LIFE, 2023; 75 (1)

In the present study, low concentrations of the very mild detergent n-dodecyl-alpha-d-maltoside in conjunction with sucrose gradient ultracentrifugati......

A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer

期刊: IUBMB LIFE, 2023; 75 (7)

Long noncoding RNAs (lncRNAs) are emerging players in cancer and they entail potential as prognostic biomarkers or therapeutic targets. Earlier studie......

The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG-related disorders

期刊: IUBMB LIFE, 2023; 75 (12)

Most eukaryotes possess a mitochondrial genome, called mtDNA. In animals and fungi, the replication of mtDNA is entrusted by the DNA polymerase ?, or ......

Anti-inflammatory effects of sodium-glucose cotransporter-2 inhibitors in COVID-19

期刊: IUBMB LIFE, 2023; 75 (8)

The ongoing pandemic of COVID-19 is intrinsically a systemic inflammatory disorder; hence, those patients suffering an underlying chronic inflammatory......

Il-6 and UGT1A1 variations may related to furosemide resistance in heart failure patients

期刊: IUBMB LIFE, 2023; 75 (10)

Furosemide is a diuretic and is used for the treatment of patients with heart failure (HF). It has been found that in some HF patients, the drug does ......

Illuminating the structure-function landscape of an evolutionary nonconserved motif in the arginases of Helicobacter gastric pathogens

期刊: IUBMB LIFE, 2023; 75 (10)

The bimetallic enzyme arginase catalyses the conversion of L-arginine to L-ornithine and urea. In Helicobacter pylori (a known human gastric pathogen)......

RNPS1 functions as an oncogenic splicing factor in cervical cancer cells

期刊: IUBMB LIFE, 2023; 75 (6)

Numerous recent studies suggest that cancer-specific splicing alteration is a critical contributor to the pathogenesis of cancer. RNA-binding protein ......

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