期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (9)
Background After binding to their corresponding receptors, cytokines mediate a variety of biological activities. However, the activity of cytokines in......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (11)
In lung adenocarcinoma (LUAD), the appearance of morphologically diverse tumor regions, termed histological patterns, is closely associated with disea......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (3)
Background Delivery systems, including peptide-based ones, that destabilize endosomes in a pH-dependent manner are increasingly used to deliver cargoe......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (4)
Background Mucopolysaccharidosis type I (MPS I) is an inherited disease caused by deficiency of the enzyme alpha-l-iduronidase (IDUA). MPS I affects s......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (2)
Introduction: Chemotherapy and radiotherapy have been reported to be basically ineffective for pancreatic ductal adenocarcinoma patients; thus, gene t......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (2)
Background Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Recent studies have demonstrated that lncRNAs play an important......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (7)
Previous studies in nephrotic syndrome have shown that three common variants in the ABCB1 gene, including rs1128503, rs2032582, and rs1045642, change ......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (10)
Background Several types of polymorphisms in vitamin D receptor (VDR) have been found in psoriasis. Aim This study looked at the role of the TaqI poly......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (12)
Background The abnormal modification of chondroitin sulfate is one of the leading causes of disease, including cancer progression. During chondroitin ......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (4)
Background Intellectual disability (ID) is a hallmark of many rare disorders that are highly heterogeneous and complex. A large number of specific gen......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (7)
Background In China, most esophageal cancer patients are squamous cell carcinomas and are treated with taxane-containing regimens; however, few studie......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (1)
Background We previously determined that polyplexes formed by linear H2K peptides were more effective in transfecting tumors in vivo than polyplexes f......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (1)
Background Circular RNA itchy E3 ubiquitin protein ligase (circ-ITCH) has previously been reported to play a key role in carcinogenesis. Nevertheless,......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (4)
Background Limb-girdle muscular dystrophy (LGMD) comprises a heterogeneous group of diseases, affecting different muscles, predominantly skeletal musc......
期刊: JOURNAL OF GENE MEDICINE, 2022; 24 (1)
Background Hypertrophic cardiomyopathy (HCM) is a hereditary disease manifested by a thickened ventricular wall. Cysteine and glycine-rich protein 3 (......