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Modulation of cytokine release from peripheral blood mononuclear cells from multiple sclerosis patients by coenzyme A and soraphen A

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 381 ()

By applying the acetyl-CoA-carboxylase inhibitors soraphen A (SorA) and coenzyme A (CoA) ex vivo, we aimed to reduce proinflammatory cytokine release ......

CD46 expression in the central nervous system of male and female pubescent mice

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 385 ()

CD46 is a complementary regulatory protein ubiquitously expressed in human cells, controlling complement system activation. CD46 has further been iden......

Weight-drop model as a valuable tool to study potential neurobiological processes underlying behavioral and cognitive changes secondary to mild traumatic brain injury

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 385 ()

The pathophysiology of post-traumatic brain injury (TBI) behavioral and cognitive changes is not fully understood, especially in its mild presentation......

Viral co-infection, autoimmunity, and CSF HIV antibody profiles in HIV central nervous system escape

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 381 ()

Antiretroviral therapy (ART) suppresses plasma and cerebrospinal fluid (CSF) HIV replication. Neurosymptomatic (NS) CSF escape is a rare exception in ......

Rituximab induces a transient fluctuation of peripheral and follicular helper T cells in neuromyelitis optica spectrum disorder

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 382 ()

Autoreactive CD4+ helper T cells are implicated in the pathogenesis of neuromyelitis optica spectrum disorder (NMOSD). Both PD-1+CXCR5+CD4+ T follicul......

Long term outcomes in patients with anti-DPPX autoimmunity

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 384 ()

DDPX antibody-associated encephalitis is characterized by cognitive dysfunction, neuropsychiatric symptoms, and CNS hyperexcitability, preceded by pro......

The case report of AQP4 and MOG IgG double positive NMOSD treated with subcutaneous Ofatumumab

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 376 ()

Neuromyelitis optica spectrum disorders (NMOSD) is an autoimmune demyelinating disease with IgG against aquaporin 4 (AQP4) in more than two thirds of ......

Atypical clinical and novel radiological findings in Susac syndrome: Experience from a large monocentric cohort

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 376 ()

Susac syndrome (SuS) is a rare immune-mediated endotheliopathy that affects the brain, retina and inner ear and is characterised by the variable clini......

Repeated mild traumatic brain injury in mice elicits long term innate immune cell alterations in blood, spleen, and brain

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 380 ()

Mild traumatic brain injury is an insidious event whereby the initial injury leads to ongoing secondary neuroand systemic inflammation through various......

Predicting the final clinical phenotype after the first attack of optic neuritis

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 381 ()

Background and objectives: To evaluate the factors determining the final clinical phenotype after an initial isolated attack of optic neuritis (ON). O......

Association between NKG2/KLR gene variants and epilepsy in Autism Spectrum Disorder

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 381 ()

Autism Spectrum Disorder (ASD) is a set of neurodevelopmental disorders mainly characterized by repetitive, restrictive and stereotypical behaviors, a......

Natural killer cells have an activated profile in early Parkinson's disease

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 382 ()

Immune dysregulation is heavily implicated in Parkinson's disease (PD) but the role of Natural Killer (NK) cells has not been well characterised. Accu......

Overlapping Epstein-Barr virus encephalitis and autoimmune glial fibrillary acidic protein astrocytopathy

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 382 ()

We describe three cases of overlapping Epstein-Barr virus (EBV) Encephalitis and Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP-A). T......

Human dendritic cell subsets in the glioblastoma-associated microenvironment

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 383 ()

Glioblastoma (GBM) is the most aggressive type of glioma (Grade IV). The presence of cytotoxic T lymphocyte (CTLs) has been associated with improved o......

Tixagevimab and cilgavimab use in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder during anti-CD20 treatment: A single-center experience

期刊: JOURNAL OF NEUROIMMUNOLOGY, 2023; 383 ()

Background: B-cell-depleting treatments, such as ocrelizumab and rituximab (anti-CD20), reduce humoral response to SARS-CoV-2 in people with Multiple ......

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