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A Literature-Based Review and Analysis of the Pharmacodynamics of the Dose Frequency of Topical 0.3% Ciprofloxacin and 0.3% Ofloxacin in the Day-1 Treatment of Bacterial Keratitis

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; 39 (1)

Purpose: To determine the appropriate dose frequency for the second-generation fluoroquinolones (2FQs), ciprofloxacin 0.3% and ofloxacin 0.3%, in the ......

The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; 39 (4)

Purpose: To evaluate the hypothesis that 3 novel compounds, OXT-328, Q-922, and CL-717 show efficacy in the treatment of oxygen-induced retinopathy (O......

ROCK Inhibitors as an Alternative Therapy for Corneal Grafting: A Systematic Review

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; 39 (9)

Currently, corneal blindness is affecting >10 million individuals worldwide, and there is a significant unmet medical need because only 1.5% of tra......

A Comparative Preclinical Evaluation of a Novel Difluprednate 0.04% BID Ophthalmic Solution and Marketed 0.05% QID Ophthalmic Emulsion

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; ()

Purpose: The purpose of this study was to compare the efficacy, and ocular pharmacokinetics of a new 0.04% w/v bis in die means twice a day (BID) opht......

Kaempferol Protects Against Retinal Photoreceptor Degeneration in a Mouse Model of Light-Induced Retinal Injury

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; 39 (1)

Purpose: Age-related macular degeneration (AMD) is a leading cause of blindness in developed countries with little in the way of treatment that preven......

A Multicenter, Randomized, Double-Blind Evaluation of the Efficacy of TJO-087 Versus 0.05% Cyclosporine A in Moderate to Severe Dry Eye

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2023; 39 (1)

Purpose: To compare the efficacy and ocular tolerability of a 0.08% nanoemulsion cyclosporine A (CsA) (TJO-087) once daily versus a conventional 0.05%......

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