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Binge drinking leads to an oxidative and metabolic imbalance in skeletal muscle during adolescence in rats: endocrine repercussion

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; ()

Binge drinking (BD) is an especially pro-oxidant model of alcohol consumption, mainly used by adolescents. It has recently been related to the hepatic......

Lipoxin A4 attenuated dexamethasone-induced muscle atrophy via activation of PGC-1α/Nrf2/TFAM pathway

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (1)

Prolonged dexamethasone (DEX) administration causes skeletal muscle atrophy through induction of both oxidative stress and mitochondrial dysfunction. ......

Differential remodeling of subcutaneous white and interscapular brown adipose tissue by long-term exercise training in aged obese female mice

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (2)

Obesity exacerbates aging-induced adipose tissue dysfunction. This study aimed to investigate the effects of long-term exercise on inguinal white adip......

RNY3 modulates cell proliferation and IL13 mRNA levels in a T lymphocyte model: a possible new epigenetic mechanism of IL-13 regulation

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (1)

Allergic asthma is the most common type of asthma. It is characterized by TH2 cell-driven inflammation in which interleukin-13 (IL-13) plays a pivotal......

Dopaminergic and adrenergic receptors synergistically stimulate browning in 3T3-L1 white adipocytes

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (1)

The browning of white adipose tissue (WAT) has attracted considerable attention in the scientific community as a popular strategy for enhancing energy......

Antidiabetic and anti-obesity properties of a polyphenol-rich flower extract from Tagetes erecta L. and its effects on Caenorhabditis elegans fat storages

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (2)

Diabetes mellitus (DM) is a metabolic disease characterized by a high blood sugar level that can cause severe complications to the organism or even de......

Nuclear-localized CTEN is a novel transcriptional regulator and promotes cancer cell migration through its downstream target CDC27

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (1)

C-terminal tensin-like (CTEN) is a tensin family protein typically localized to the cytoplasmic side of focal adhesions, and primarily contributes to ......

Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (2)

NOX5 is the last member of the NADPH oxidase (NOXs) family to be identified and presents some specific characteristics differing from the rest of the ......

Metabolic dysfunction-associated fatty liver disease (MAFLD): an update of the recent advances in pharmacological treatment

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (4)

Metabolic dysfunction-associated fatty liver disease (MAFLD) is nowadays considered the liver manifestation of metabolic syndrome. Its prevalence is i......

Neurobehavioral, biochemical and histological assessment of the effects of resveratrol on cuprizone-induced demyelination in mice: role of autophagy modulation

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (3)

Resveratrol is known to exhibit neuroprotective effects in many neurological disorders via autophagy modulation. However, controversial results have b......

Study of hydrogen sulfide biosynthesis in synovial tissue from diabetes-associated osteoarthritis and its influence on macrophage phenotype and abundance

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (3)

Type 2 diabetes (DB) is an independent risk factor for osteoarthritis (OA). However, the mechanisms underlying the connection between both diseases re......

Melatonin controls cell proliferation and modulates mitochondrial physiology in pancreatic stellate cells

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (1)

We have investigated the effects of melatonin on major pathways related with cellular proliferation and energetic metabolism in pancreatic stellate ce......

Extracellular histones trigger oxidative stress-dependent induction of the NF-kB/CAM pathway via TLR4 in endothelial cells

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (2)

Extracellular histones have been reported to aggravate different pathophysiological processes by increasing vascular permeability, coagulopathy, and i......

Editorial Special Issue: 2021 consortium for trans-pyrenean investigations on obesity and diabetes

期刊: JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2023; 79 (2)

This Special Issue of the Journal of Physiology and Biochemistry contains 7 contributions that have been elaborated in the context of the mini-network......

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