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In silico and in vitro studies of potential inhibitors against Dengue viral protein NS5 Methyl Transferase from Ginseng and Notoginseng

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (1)

Background and aim: Dengue is a potentially deadly tropical infectious disease transmitted by mosquito vector Aedes aegypti with no antiviral drug ava......

Cinnamic aldehyde, an anti-inflammatory component in Du-Huo-Ji- Sheng-Tang, ameliorates arthritis in II collagenase and monosodium iodoacetate induced osteoarthritis rat models

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (1)

Background and aim: Du-Huo-Ji-Sheng-Tang (DHJST) is a Chinese herbal formula used for arthralgia and arthritis treatment clinically. This study aims t......

Modulators of diabetic neuropathy and inflammation from Saponaria officinalis: Isolation of active phytochemicals and potential mechanisms of action

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (3)

Background and aim: Natural metabolites are rich in neuroactive and anti-inflammatory phytochemicals. Soapwort or Saponaria officinalis (Sap) has been......

Coptis chinensis, and extracts of guava and mulberry leaves present good inhibiting potential on obesity and associated metabolic disorders in high-fat diet obesity mice model

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (3)

This study aimed to investigate the anti-obesity effects of Coptis chinensis (CC), BALASAN (combinational guava leaf extract and mulberry leaf extract......

Wound healing potential of Acacia catechu in streptozotocin-induced diabetic mice using in vivo and in silico approach

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (5)

Background and aim: Acacia catechu Wild. (Fabaceae) barks are traditionally used in the treatment of diabetes and wounds. Therefore, the objective of ......

Gastroprotective effects of Machilus zuihoensis Hayata bark against acidic ethanol-induced gastric ulcer in mice

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (5)

Background and aim: In traditional medicine, Machilus zuihoensis Hayata bark (MZ) is used in combination with other medicines to treat gastric cancer,......

Ziqi Dihuang decoction ameliorates thrombosis in septic rats by inhitbiting plasminogen activator inhibitor-1

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (6)

Introduction: Sepsis is now a global medical burden with high morbility and mortality. The focus of this study was to evaluate the effects of Ziqi Dih......

Baicalin inhibits the replication of the hepatitis B virus by targeting TRIM25

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (6)

Objective: Baicalin, which is a key bioactive constituent obtained from Scutellaria baicalensis, has been utilized in traditional Chinese medicine for......

Dual actions of gallic acid and andrographolide trigger AdipoR1 to stimulate insulin secretion in a streptozotocin-induced diabetes rat model

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (1)

Common treatments for the management of diabetes have limitations due to side effects, hence the need for continuous research to discover new remedies......

Acupuncture is associated with reduced dementia risk in patients with insomnia: A propensity-score-matched cohort study of real-world data

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (3)

Background and aim: Insomnia is a subjective illness that has been identified as a risk factor for dementia. In this study, we investigated the associ......

Antihyperglycemic and anti-type 2 diabetic activity of marine hydroquinone isolated from brown algae (Dictyopteris polypodioides)

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (4)

Background and aims: Brown algae (Dictyopteris polypodioides) extract (DP) presented high inhibitory potential against a -amylase. The present study a......

Barleria prionitis L. extracts ameliorate doxorubicin-induced acute kidney injury via modulation of oxidative stress, inflammation, and apoptosis

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (5)

Background and aim: Doxorubicin (DOX) is a chemotherapeutic drug with potential nephrotoxic effects on patients who are on cancer chemotherapy. An int......

Spatholobus suberectus inhibits lipogenesis and tumorigenesis in triple-negative breast cancer via activation of AMPK-ACC and K-Ras- ERK signaling pathway

期刊: JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE, 2023; 13 (6)

Background and aim: Triple-negative breast cancer (TNBC) is a highly invasive type of breast cancer with a poor prognosis. Currently, there are no eff......

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