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Cystic Renal Lesions: A Systematic Review of Diagnosis and Treatment

期刊: KIDNEY CANCER, 2023; 7 (1)

BACKGROUND: Renal cysts are the most frequently occurring incidental renal lesions. They are asymptomatic, which explains why they tend to be diagnose......

Influences of Age and Comorbidities on Indication for Partial Nephrectomy: A Systematic Review

期刊: KIDNEY CANCER, 2023; 7 (1)

BACKGROUND: The influence of age and comorbidities during decision-making for patients with renal cell carcinoma remains controversial. OBJECTIVE: To ......

Fibrinogen Levels in Patients with Metastatic Renal Cell Carcinoma Treated with Nivolumab: Results of a Multicenter Prospective Trial

期刊: KIDNEY CANCER, 2023; 7 (1)

Background: Introduction of immune checkpoint inhibitors in the standard of care for metastatic renal cell carcinoma (mRCC) requires robust but yet si......

Axitinib beyond first-line therapy of Metastatic Renal Cell Carcinoma: Real World Data from the STAR-TOR registry

期刊: KIDNEY CANCER, 2023; 7 (1)

Objective: To evaluate the effectiveness and safety profile of the tyrosine kinase inhibitor Axitinib for patients with advanced or metastatic renal c......

Nephrotoxicity Associated with Contemporary Renal Cell Carcinoma Regimens: A Systematic Review and Meta-Analysis

期刊: KIDNEY CANCER, 2023; 7 (1)

Background: The nephrotoxicity profile of contemporary first-line regimens for treatment of metastatic renal cell carcinoma (mRCC) has not been system......

Targeted Literature Review of Outcomes to Initial Systemic Therapy for Advanced/Metastatic Non-Clear Cell Renal Cell Carcinoma in Observational Studies

期刊: KIDNEY CANCER, 2023; 7 (1)

Background: Non-clear cell renal cell carcinoma (nccRCC) is a diverse group of cancers that occurs in approximately 25% of patients with renal cell ca......

MET Inhibitors for Papillary Renal Cell Carcinoma

期刊: KIDNEY CANCER, 2023; 7 (1)

BACKGROUND: Papillary renal cell carcinoma (PRCC) has a relatively poor prognosis in the metastatic setting. In contrast to clear cell kidney cancer, ......

Efficacy of Therapy vs Surveillance in Patients with Resected Early-Stage Intermediate to High-Risk Renal Cell Carcinoma

期刊: KIDNEY CANCER, 2023; 7 (1)

BACKGROUND: The historical standard of care for locally advanced renal cell carcinoma (RCC) is nephrectomy + active surveillance. Despite a high recur......

Antigenic targets in clear cell renal cell carcinoma

期刊: KIDNEY CANCER, 2023; 7 (1)

Immune checkpoint inhibitors (ICIs) have transformed the management of advanced renal cell carcinoma (RCC), but most patients still do not receive a l......

Adjuvant Therapy in Renal Cell Carcinoma: Are we ready for prime time?

期刊: KIDNEY CANCER, 2023; 7 (1)

The standard of care for localized renal cell carcinoma (RCC) is radical or partial nephrectomy. Despite complete resection, a subset of patients will......

Genomic and Transcriptomic Characteristics of Tumors of Patients with Metastatic Clear Cell Renal Cell Carcinoma Clinically Benefiting from First-Line Treatment with Ipilimumab Plus Nivolumab

期刊: KIDNEY CANCER, 2023; 7 (1)

Background: Ipilimumab plus nivolumab is approved as a first-line treatment for intermediate or poor risk metastatic renal cell carcinoma (mRCC). Howe......

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