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Manufactured tissue-to-tissue barrier chip for modeling the human blood-brain barrier and regulation of cellular trafficking

期刊: LAB ON A CHIP, 2023; 23 (13)

Microphysiological system or organ-on-a-chip technologies can replicate the key structure and function of 3D human tissues with higher reproducibility......

In situ transmission electron microscopy as a toolbox for the emerging science of nanometallurgy

期刊: LAB ON A CHIP, 2023; 23 (14)

Potential applications of nanomaterials range from electronics to environmental technology, thus a better understanding of their manufacturing and man......

Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

期刊: LAB ON A CHIP, 2023; 23 (16)

Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled architectures that repeatedly achieve biomimicry of biological ph......

Microfluidic device with reconfigurable spatial temporal gradients reveals plastic astrocyte response to stroke and reperfusion

期刊: LAB ON A CHIP, 2023; 23 (18)

As a leading cause of mortality and morbidity, stroke constitutes a significant global health burden. Ischemic stroke accounts for 80% of cases and oc......

A versatile artificial skin platform for sweat sensor development

期刊: LAB ON A CHIP, 2023; 23 (9)

Research targeting the development of on-body sensors has been significantly growing in recent years - an example is on-skin sweat sensing. However, t......

Digital microfluidics with distance-based detection - a new approach for nucleic acid diagnostics

期刊: LAB ON A CHIP, 2023; 24 (1)

There is great enthusiasm for using loop-mediated isothermal amplification (LAMP) in point-of-care nucleic acid amplification tests (POC NAATs), as an......

Parallel detection of chemical reactions in a microfluidic platform using hyperpolarized nuclear magnetic resonance

期刊: LAB ON A CHIP, 2023; 23 (23)

The sensitivity of NMR may be enhanced by more than four orders of magnitude via dissolution dynamic nuclear polarization (dDNP), potentially allowing......

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

期刊: LAB ON A CHIP, 2023; 24 (1)

We present tuna-step, a novel microfluidic module based on step emulsification that allows for reliable generation of droplets of different sizes. Unt......

A microfluidic double emulsion platform for spatiotemporal control of pH and particle synthesis

期刊: LAB ON A CHIP, 2023; 23 (20)

The temporal control of pH in microreactors such as emulsion droplets plays a vital role in applications including biomineralisation and microparticle......

Proof-of-concept optimization of a copper-mediated 18F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation

期刊: LAB ON A CHIP, 2023; 23 (21)

Copper-mediated radiofluorination has demonstrated remarkable potential in forming aromatic C-F-18 bonds of radioligands for positron emission tomogra......

Microfabricated acoustofluidic membrane acoustic waveguide actuator for highly localized in-droplet dynamic particle manipulation

期刊: LAB ON A CHIP, 2023; 23 (7)

Precision manipulation techniques in microfluidics often rely on ultrasonic actuators to generate displacement and pressure fields in a liquid. Howeve......

A monolithic microfluidic probe for ambient mass spectrometry imaging of biological tissues

期刊: LAB ON A CHIP, 2023; 23 (21)

Ambient mass spectrometry imaging (MSI) is a powerful technique that allows for the simultaneous mapping of hundreds of molecules in biological sample......

Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme

期刊: LAB ON A CHIP, 2023; 23 (13)

Droplet injection strategies are a promising tool to reduce the large amount of sample consumed in serial femtosecond crystallography (SFX) measuremen......

Bridging the gap between tumor-on-chip and clinics: a systematic review of 15 years of studies

期刊: LAB ON A CHIP, 2023; 23 (18)

Over the past 15 years, the field of oncology research has witnessed significant progress in the development of new cell culture models, such as tumor......

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