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Circ_0057583 facilitates brain microvascular endothelial cell injury through modulating miR-204-5p/NR4A1 axis

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (2)

Lipopolysaccharide (LPS) can induce vascular endothelial injury. Circular RNAs (circRNAs) have been verified to regulate different cellular processes ......

JIF:3.228

Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (4)

Allergic asthma is characterized by chronic airway inflammation and is constantly associated with anxiety disorder. Recent studies showed bidirectiona......

JIF:3.228

Evaluation of Styrylbenzene analog- FSB and its affinity to bind parenchymal plaques and tangles in patients of Alzheimer's disease

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (3)

Although several histochemical markers for senile plaques (SP) and neurofibrillary tangles (NFTs) have been synthesized since the discovery of plaques......

JIF:3.228

Ligustilide ameliorates cognitive impairment via AMPK/SIRT1 pathway in vascular dementia rat

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (5)

Vascular dementia (VaD) is the second cause of dementia after Alzheimer's disease. Ligustilide (LIG) is one of the main active ingredients of traditio......

JIF:3.228

Neuroprotective effects of 18 beta-glycyrrhetinic acid against bisphenol A-induced neurotoxicity in rats: involvement of neuronal apoptosis, endoplasmic reticulum stress and JAK1/STAT1 signaling pathway

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (6)

The exposure to bisphenol A (BPA) is inevitable owing to its common use in the production of polycarbonate plastics. Studies to reduce side effects ar......

JIF:3.228

LncRNA ZFAS1 regulates the hippocampal neurons injury in epilepsy through the miR-15a-5p/OXSR1/NF-kappa B pathway

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (7)

Long non-coding RNAs (lncRNAs) have been confirmed to be involved in epilepsy development. It has been reported that lncRNA ZFAS1 plays a vital regula......

JIF:3.228

Exogenous hydrogen sulfide restores CSE and CBS but no 3-MST protein expression in the hypothalamus and brainstem after severe traumatic brain injury

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (6)

Hydrogen sulfide (H2S) is a gasotransmitter endogenously synthesized by cystathionine-gamma-lyase (CSE), cystathionine-beta-synthase (CBS), and 3-merc......

JIF:3.228

An aqueous extract of Syzygium cumini protects against kainate-induced status epilepticus and amnesia: evidence for antioxidant and anti-inflammatory intervention

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (7)

Temporal lobe epilepsy is the most common drug-resistant epilepsy. To cure epilepsy, drugs must target the mechanisms at the origin of seizures. Thus,......

JIF:3.228

The effect of chronic stress and its preconditioning on spatial memory as well as hippocampal LRP1 and RAGE expression in a streptozotocin-induced rat model of Alzheimer's disease

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (8)

According to available evidence, prolonged or chronic exposure to stress is detrimental to various brain structures, including the hippocampus. The cu......

JIF:3.228

Peroxisome proliferator-activated receptor-gamma doesn't modify altered electrophysiological properties of the CA1 pyramidal neurons in a rat model of hepatic cirrhosis

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (8)

Regarding the low quality of life due to the cognitive complications in the patients with hepatic cirrhosis (HC), the goal of this study was to examin......

JIF:3.228

Vitamin D-3 supplementation ameliorates cognitive impairment and alters neurodegenerative and inflammatory markers in scopolamine induced rat model

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (8)

A multifaceted approach can be effective for the treatment of dementia including the most common form, Alzheimer's disease (AD). However, currently, i......

JIF:3.228

Serum fractalkine and 3-nitrotyrosine levels correlate with disease severity in Parkinson's disease: a pilot study

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (1)

Parkinson's disease (PD) and Parkinsonian syndromes; Progressive supranuclear palsy (PSP), and Multiple system atrophy (MSA) are debilitating neurodeg......

JIF:3.228

Adult human neurogenesis: early studies clarify recent controversies and go further

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (1)

Evidence on adult mammalian neurogenesis and scarce studies with human brains led to the idea that adult human neurogenesis occurs in the subgranular ......

JIF:3.228

Association between genetic variants and risk of obsessive-compulsive disorder

期刊: METABOLIC BRAIN DISEASE, 2022; 37 (2)

Obsessive-compulsive disorder (OCD) is a complex multi-gene disorder. In the current study, we genotyped six single nucleotide polymorphisms (SNPs) wi......

JIF:3.228

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