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Nitric Oxide(II) in the Biology of Chlorophyta

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

NO is a gaseous signaling redox-active molecule that functions in various eukaryotes. However, its synthesis, turnover, and effects in cells are speci......

Genes Associated with Increased Stress Sensitivity in Hypertensive ISIAH Rats

期刊: MOLECULAR BIOLOGY, 2023; 57 (2)

Inherited stress-induced arterial hypertension (ISIAH) rats are characterized by increased stress reactivity of the hypothalamic-pituitary-adrenal and......

Identification of Functionally Significant Polymorphic Variants in miRNA Genes in Carotid Atherosclerosis

期刊: MOLECULAR BIOLOGY, 2023; 57 (3)

miRNAs are vital molecules of gene expression. They are involved in the pathogenesis of various common diseases, including atherosclerosis, its risk f......

Spatial Models of Piezo Proteins and Protein-Protein Interaction Networks in Trichoplax Animals (Placozoa)

期刊: MOLECULAR BIOLOGY, 2023; 57 (5)

The marine free-living organism Trichoplax (phylum Placozoa) resembles a unicellular amoeba in shape and type of movement. Trichoplax diverged from th......

Long Noncoding RNAs MEG3, TUG1, and hsa-miR-21-3p Are Potential Diagnostic Biomarkers for Coronary Artery Disease

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

Peripheral blood biomarkers are of particular importance to diagnose certain diseases including coronary artery disease (CAD) due to their non-invasiv......

Abnormal mTOR Signaling Pathway Activity in Autism Spectrum Disorders: Prospects of Mechanism-Based Therapy

期刊: MOLECULAR BIOLOGY, 2023; 57 (2)

Autism spectrum disorder (ASD) is a developmental disorder characterized by the early onset of problems with communication, learning, and behavior. Th......

Molecular and Cellular Aspects of the Endothelial-Mesenchymal Transition in Cardiovascular Diseases

期刊: MOLECULAR BIOLOGY, 2023; 57 (4)

Endothelial cells (ECs), which form the inner surface of the blood vessels, contact the blood, withstand mechanical pressure, and demonstrate heteroge......

Metabolic Stress of Red Blood Cells Induces Hemoglobin Glutathionylation

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

Metabolic stress caused by a lack of glucose significantly affects the state of red blood cells, where glycolysis is the main pathway for the producti......

The Protective Action of Hsp70 and Hydrogen Sulfide Donors in THP-1 Macrophages in the Lipopolysaccharide-Induced Inflammatory Response by Modulating Endocytosis

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

Hsp70 and hydrogen sulfide donors reduce inflammatory processes in human and animal cells. The biological action mediated by Hsp70 and H2S donors (GYY......

Potential of Interferon Lambda as an Inhibitor of SARS-CoV-2

期刊: MOLECULAR BIOLOGY, 2023; 57 (2)

This study provides an overview of scientific results on the feasibility of using type III interferons against SARS-CoV-2. We have analyzed data obtai......

Metabolic Heterogeneity of Tumors

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

Currently, much attention in oncology is devoted to the issues of tumor heterogeneity, which creates serious problems in the diagnosis and therapy of ......

The Effect of the Knockout of Major Transsulfuration Genes on the Pattern of Protein Synthesis in D. melanogaster

期刊: MOLECULAR BIOLOGY, 2023; 57 (1)

The enzymes involved in the transsulfuration pathway and hydrogen sulfide production-cystathionine-beta-synthase (CBS), cystathionine-gamma-lyase (CSE......

Heat Shock Proteins in Plant Protection from Oxidative Stress

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

This review considers the recent progress on the role of heat shock proteins (HSPs), as well as transcription factors of heat shock proteins genes (HS......

The Antioxidant and Geroprotective Properties of an Extract of Mountain Ash (Sorbus aucuparia L.) Fruits

期刊: MOLECULAR BIOLOGY, 2023; 57 (6)

Plant polyphenols are characterized by a wide range of biological activities, including antioxidant properties, and have a high geroprotective potenti......

How Histone Deacetylase 3 Controls Hepcidin Expression and Hepatitis C Virus Replication

期刊: MOLECULAR BIOLOGY, 2023; 57 (3)

The key role of histone deacetylases (HDAC) in the regulation of the cellular response to infection with the hepatitis C virus (HCV) was first demonst......

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