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The Trend of CRISPR-Based Technologies in COVID-19 Disease: Beyond Genome Editing

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (2)

Biotechnological approaches have always sought to utilize novel and efficient methods in the prevention, diagnosis, and treatment of diseases. This sc......

Regulatory Roles of MicroRNAs in the Pathogenesis of Metabolic Syndrome

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Metabolic syndrome refers to a group of several disease conditions together with high glucose triglyceride levels, high blood pressure, lower high-den......

A Short Review on Current Status and Obstacles in the Sustainable Production of Biohydrogen from Microalgal Species

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Biohydrogen is an economical fuel which has enormous promise as an alternative energy source. The synthesis of biohydrogen can be done more affordably......

Effects of Zofenopril on Arterial Stiffness in Hypertension Patients

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Angiotensin-converting enzyme inhibitors (ACEIs) reduce arterial stiffness beyond their antihypertensive effect. Studies showed that sulfhydryl ACEIs ......

Optimizing the Metal Bioreduction Process in Recombinant Shewanella azerbaijanica Bacteria: A Novel Approach via mtrC Gene Cloning and Nitrate-Reducing Pathway Destruction

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Environmental pollution is growing every day in terms of the increase in population, industrialization, and urbanization. Shewanella azerbaijanica is ......

k- Strong Inference Algorithm: A Hybrid Information Theory Based Gene Network Inference Algorithm

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Gene networks allow researchers to understand the underlying mechanisms between diseases and genes while reducing the need for wet lab experiments. Nu......

Heterologous Expression of Codon-Optimized Azurin Transferred by Magnetofection Method in MCF-10A Cells

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Transfection efficiency of the immortalized human breast epithelial cell line MCF-10A remains an issue that needs to be resolved. In this study, it wa......

Tropical Seaweeds as a Sustainable Resource Towards Circular Bioeconomy: Insights and Way Forward

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Seaweeds are photosynthetic marine macroalgae known for their rapid biomass growth and their significant contributions to global food and feed product......

Recombinant Adeno-associated Viral Vectors Serotypes 6 and 9 are Able to Transduce Human Tracheal Epithelial Cells but Not Human Induced Pluripotent Stem Cells

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (9)

Recombinant adeno-associated viruses (rAAVs) may be useful for the development of gene therapy for hereditary diseases. Patient-specific human induced......

Structure-Based Virtual Screening and Discovery of New Bi-functional DAPK1 Inhibitors

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

Recently, a new signaling complex Death-Associated Protein Kinase 1 (DAPK1)-N-methyl D-aspartate receptor subtype 2B (NR2B) engaged in the neuronal de......

Peptide-Based Therapeutics in Cancer Therapy

期刊: MOLECULAR BIOTECHNOLOGY, 2023; ()

A monster called cancer is still one of the most challenging human problems and one of the leading causes of death in the world. Different types of tr......

CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (2)

Genetic studies of familial forms of Parkinson's disease (PD) have shown that the ZNF543 gene is a candidate gene that operates relevant to this disea......

Application of an Autoinduction Strategy to Optimize the Heterologous Production of an Antitumor Bispecific Fusion Protein Based on the TRAIL Receptor-Selective Mutant Variant in Escherichia coli

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (4)

Autoinduction is a simple approach for heterologous protein expression that helps to achieve the high-level production of recombinant proteins in solu......

Molecular Cloning, Expression, Sequence Characterization and Structural Insight of Bubalus bubalis Growth Hormone-Receptor

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (7)

The current study focuses on molecular cloning, expression and structural characterization of growth hormone-receptor (GHR) and its extracellular doma......

Recent Advances in Antibiotic-Free Markers; Novel Technologies to Enhance Safe Human Food Production in the World

期刊: MOLECULAR BIOTECHNOLOGY, 2023; 65 (7)

Crops that have been genetically modified (GM) include additional beneficial traits that present fresh approaches to boosting yield productivity and s......

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