期刊: MOLECULAR DIVERSITY, 2023; 27 (3)
In this study, FDA-approved HCV antiviral drugs and their structural analogues-several of them in clinical trials-were tested for their inhibitory pro......
期刊: MOLECULAR DIVERSITY, 2023; 27 (4)
To fight against the devastating coronavirus disease 2019 (COVID-19), identifying robust anti-SARS-CoV-2 therapeutics from all possible directions is ......
期刊: MOLECULAR DIVERSITY, 2023; 27 (4)
In the polyol pathway, aldose reductase (AR) catalyzes the formation of sorbitol from glucose. In order to detoxify some dangerous aldehydes, AR is es......
期刊: MOLECULAR DIVERSITY, 2023; 27 (5)
Various boron-containing isocyanides have been efficiently synthesized from the corresponding enantiopure beta-substituted beta-amino boronic acid pin......
期刊: MOLECULAR DIVERSITY, 2023; ()
Phosphoinositide kinases (PIKs) are a type of lipid kinase that acts as an upstream activator of oncogenic signaling. Presently accessible therapeutic......
期刊: MOLECULAR DIVERSITY, 2023; ()
Solving the worldwide problem of growing bacterial drug resistance will require a short-run and medium-term strategy. Structure-activity relationship ......
期刊: MOLECULAR DIVERSITY, 2023; ()
Marburg virus disease (MVD) is caused by the Marburg virus, a one-of-a-kind zoonotic RNA virus from the genus Filovirus. Thus, this current study empl......
期刊: MOLECULAR DIVERSITY, 2023; ()
In this research the goal was to produce novel pyrimidine triazole compounds in high yields using triethylamin as an efficient catalyst. These new com......
期刊: MOLECULAR DIVERSITY, 2023; 27 (2)
The coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is affecting human life in an unprecede......
期刊: MOLECULAR DIVERSITY, 2023; 27 (2)
The human DNA repair enzyme AlkB homologue-2 (ALKBH2) repairs methyl adducts from genomic DNA. Overexpression of ALKBH2 has been implicated in both tu......
期刊: MOLECULAR DIVERSITY, 2023; 27 (3)
A new method is designed for the synthesis of some novel methyl 3-aryl/alkyl-4-cinnolinecarboxylate with developed a general Richter cyclization throu......
期刊: MOLECULAR DIVERSITY, 2023; 27 (5)
The unique therapeutic and biological characteristics of spirooxindole have led to the presentation of numerous reactions for the synthesis of spiroox......
期刊: MOLECULAR DIVERSITY, 2023; 27 (4)
Due to the lack of effective vaccine(s) against leishmania and also pharmacokinetics issues of current drugs, it is necessary to discover new antileis......
期刊: MOLECULAR DIVERSITY, 2023; 27 (3)
Trifluoroacetic acid (TFA), due to its strong acidity and low boiling point, is extensively used in protecting groups-based synthetic strategies. Inde......
期刊: MOLECULAR DIVERSITY, 2023; 27 (5)
To date, many HDAC6 inhibitors have been identified and developed but none is clinically approved as of now. Through this study, we aim to obtain nove......