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Caught in the act: In situ visualization of bacterial secretion systems by cryo-electron tomography

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Bacterial secretion systems, such as the type 3, 4, and 6 are multiprotein nanomachines expressed at the surface of pathogens with Gram-negative like ......

Negative regulation of biofilm development by the CUG-Ser1 clade-specific histone H3 variant is dependent on the canonical histone chaperone CAF-1 complex in Candida albicans

期刊: MOLECULAR MICROBIOLOGY, 2023; 119 (5)

The CUG-Ser1 clade-specific histone H3 variant (H3V(CTG)) has been reported to be a negative regulator of planktonic to biofilm growth transition in C......

Cyclic di-GMP signaling-Where did you come from and where will you go?

期刊: MOLECULAR MICROBIOLOGY, 2023; 120 (4)

Microbes including bacteria are required to respond to their often continuously changing ecological niches in order to survive. While many signaling m......

Where is the EXIT? Phenotypic screens for new egress factors in apicomplexan parasites

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Apicomplexans, such as Plasmodium and Toxoplasma are obligate intracellular parasites that invade, replicate and finally EXIT their host cell. During ......

Lipidome remodeling in response to nutrient replenishment requires the tRNA modifier Deg1/Pus3 in yeast

期刊: MOLECULAR MICROBIOLOGY, 2023; 120 (6)

In the yeast Saccharomyces cerevisiae, the absence of the pseudouridine synthase Pus3/Deg1, which modifies tRNA positions 38 and 39, results in increa......

Putative prefoldin complex subunit 5 of Plasmodium berghei is crucial for microtubule formation and parasite development in the mosquito

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Plasmodium sporozoite development in and egress from oocysts in the Anopheles mosquito remains largely enigmatic. In a previously performed high-throu......

Prophage excision switches the primary ribosome rescue pathway and rescue-associated gene regulations in Escherichia coli

期刊: MOLECULAR MICROBIOLOGY, 2023; 119 (1)

Escherichia coli has multiple pathways to release nonproductive ribosome complexes stalled at the 3 & PRIME; end of nonstop mRNA: tmRNA (SsrA RNA)......

Lack of evidence that Pseudomonas aeruginosa AmpDh3-PA0808 constitute a type VI secretion system effector-immunity pair

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Type VI secretion systems (T6SSs) are cell envelope-spanning protein complexes that Gram-negative bacteria use to inject a diverse arsenal of antibact......

Evidence that the PatB (CnfR) factor acts as a direct transcriptional regulator to control heterocyst development and function in the cyanobacterium Nostoc PCC 7120

期刊: MOLECULAR MICROBIOLOGY, 2023; 119 (4)

Under nitrogen-limiting conditions, the filamentous cyanobacterium Nostoc PCC7120 differentiates nitrogen-fixing heterocysts at semi-regular intervals......

The Mba1 homologue of Trypanosoma brucei is involved in the biogenesis of oxidative phosphorylation complexes

期刊: MOLECULAR MICROBIOLOGY, 2023; 119 (5)

Consistent with other eukaryotes, the Trypanosoma brucei mitochondrial genome encodes mainly hydrophobic core subunits of the oxidative phosphorylatio......

Molecular mapping of virus-infected cells with immunogold and metal-tagging transmission electron microscopy

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Transmission electron microscopy (TEM) has been essential to study virus-cell interactions. The architecture of viral replication factories, the princ......

Differential survival of Staphylococcal species in macrophages

期刊: MOLECULAR MICROBIOLOGY, 2023; ()

Staphylococcus aureus is considered an extracellular pathogen, yet the bacterium is able to survive within and escape from host cells. An agr/sae muta......

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