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Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 92 ()

Glaucoma is a common, complex, multifactorial neurodegenerative disease characterized by progressive dysfunction and then loss of retinal ganglion cel......

Role of Siglecs in viral infections: A double-edged sword interaction

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 90 ()

Sialic-acid-binding immunoglobulin-like lectins are cell surface immune receptors known as Siglecs that play a paramount role as modulators of immunit......

The changing epidemiology of fungal infections

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 94 ()

Invasive fungal diseases are common complications in critically ill patients and in those with significant underlying imbalanced immune systems. Funga......

Human colonic catabolism of dietary flavan-3-ol bioactives

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 89 ()

Understanding the fate of ingested polyphenols is crucial in elucidating the molecular mechanisms underlying the beneficial effects of a fruit and veg......

Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 94 ()

In the last years, neuroprotective therapies have attracted the researcher interests as modern and challenging approach for the treatment of neurodege......

Practical issues related to non-Aspergillus invasive mold infections

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 94 ()

Infection by non-Aspergillus molds has been increasingly reported. The management of such infections is challenging both for diagnosis and treatment, ......

Current understanding of genetics and epigenetics in pseudoexfoliation syndrome and glaucoma

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 94 ()

Pseudoexfoliation is a complex, progressive, and systemic age-related disorder. The early stage of deposition of extracellular fibrillar material on o......

Non-canonical roles of Siglecs: Beyond sialic acid-binding and immune cell modulation

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 90 ()

Siglecs (Sialic acid-binding immunoglobulin-type lectins) are I-type lectins that bind with sialic acid ligands (Sia). Most are expressed on the surfa......

Perspectives for the application of neurogenetic research in programming Neurorehabilitation

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 91 ()

Certain genetic variants underlie the proper functioning of the nervous system. They affect the nervous system in all aspects - molecular, systemic, c......

Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 89 ()

Ellagitannins (ETs) and ellagic acid (EA) are dietary polyphenols poorly absorbed but extensively metabolized by the human gut microbiota to produce d......

CD33 isoforms in microglia and Alzheimer's disease: Friend and foe

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 90 ()

Alzheimer's disease (AD) is the most common form of neurodegenerative disease and is considered the main cause of dementia worldwide. Genome-wide asso......

Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 93 ()

Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis, resulting from the excessive deposition of collagen fib......

Microorganisms-derived antigens for preventive anti-cancer vaccines

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 92 ()

Cancer prevention is one of the aim with the highest priority in order to reduce the burden of cancer diagnosis and treatment on individuals as well a......

Kidney fibrosis: Emerging diagnostic and therapeutic strategies

期刊: MOLECULAR ASPECTS OF MEDICINE, 2023; 93 ()

An increasing number of patients worldwide suffers from chronic kidney disease (CKD). CKD is accompanied by kidney fibrosis, which affects all compart......

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