期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (2)
Ramp sequences occur when the average translational efficiency of codons near the 5 ' end of highly expressed genes is significantly lower than the re......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
Protein-DNA binding is of a great interest due to its importance in many biological processes. Previous studies have presented many factors responsibl......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
Whole-genome sequencing has facilitated genome-wide analyses of association, prediction and heritability in many organisms. However, such analyses in ......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
BRCA1 germline mutation carriers are predisposed to breast cancers. Epigenomic regulations have been known to strongly interact with genetic variation......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (3)
With the upcoming of affordable Next-Generation Sequencing technologies, the number of known non-protein coding RNAs increased drastically in recent y......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
Cell-free (cf)DNA signatures are quickly becoming the target of choice for non-invasive screening, diagnosis, treatment and monitoring of human tumors......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (2)
Advancing technologies that quantify gene expression in space are transforming contemporary biology research. A class of spatial transcriptomics metho......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
We present a structure-based method for finding and evaluating structural similarities in protein regions relevant to ligand binding. PDBspheres compr......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
DNA methylation is an epigenetic mark implicated in crucial biological processes. Most of the knowledge about DNA methylation is based on bulk experim......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
HKG is the first fully accessible variant database for Hong Kong Cantonese, constructed from 205 novel whole-exome sequencing data. There has long bee......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
A main strategy of bacteria adapting to environmental changes is the remodeling of their transcriptome. Changes in the transcript levels of specific g......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (1)
Effective embedding is actively conducted by applying deep learning to biomolecular information. Obtaining better embeddings enhances the quality of d......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (2)
Nanopore sequencing, also known as single-molecule real-time sequencing, is a third/fourth generation sequencing technology that enables deciphering s......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (3)
Recent advances in sequencing and bioinformatics have expanded the tree of life by providing genomes for uncultured environmentally relevant clades, e......
期刊: NAR GENOMICS AND BIOINFORMATICS, 2022; 4 (4)
Epstein-Barr virus (EBV) is a widely prevalent human herpes virus infecting over 95% of all adults and is associated with a variety of B-cell cancers ......