期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (1)
The endosomal sorting complex required for transport (ESCRT) is a highly conserved protein machinery that drives a divers set of physiological and pat......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (4)
Endogenous retroviruses (ERVs), a type of transposable element (TE), have been incorporated throughout evolution into the human genome. We show that m......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (5)
Transcriptional bursting has been linked to the stochastic positioning of nucleosomes. However, how bursting is regulated by the remodeling of promote......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (5)
Single-molecule live-cell imaging of the transcription dynamics in budding yeast cells revealed that the remodeling of different nucleosomes in the pr......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; ()
In mammals, the kidney plays an essential role in maintaining blood homeostasis through the selective uptake, retention or elimination of toxins, drug......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; ()
Pioneer transcription factors access gene regulatory sites embedded within chromatin. They drive gene expression programs vital for cell fate decision......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (7)
The activity of genes is controlled by regulatory DNA sequences, which interact and communicate with their target genes over long genomic distances. N......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; ()
Here, the authors show that although transcription is severely diminished in nucleated erythrocytes, it persists at genes involved in promoter-proxima......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (9)
Translation affects messenger RNA stability and, in yeast, this is mediated by the Ccr4-Not deadenylation complex. The details of this process in mamm......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (9)
In January 2024, Nature Structural & Molecular Biology (NSMB) will celebrate the 30th anniversary of publishing its first issue. Though initially ......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; ()
The androgen receptor forms nuclear condensates associated with gene transcription. Investigating the molecular basis of condensate formation led us t......
期刊: NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023; 30 (6)
Triose phosphates (TPs) are the primary products of photosynthetic CO2 fixation in chloroplasts, which need to be exported into the cytosol across the......