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Evaluating the toxic mechanism of 1,2-diacetylbenzene in neural cells/ tissues: The favorable impact of silibinin

期刊: NEUROTOXICOLOGY, 2023; 99 ()

1,2-diacetylbenzene (1,2-DAB) is a neurotoxic component of aromatic solvents commonly used in industrial applications that induces neuropathological c......

Toxicity and behavioural effects of ocfentanil and 2-furanylfentanyl in zebrafish larvae and mice

期刊: NEUROTOXICOLOGY, 2023; 95 ()

The introduction of the so-called New Psychoactive Substances represents a problem of global concern due to several factors, including multiplicity of......

Longitudinal effects of ketamine on cell proliferation and death in the CNS of zebrafish

期刊: NEUROTOXICOLOGY, 2023; 97 ()

Zebrafish is known for its widespread neurogenesis and regenerative capacity, as well as several biological ad-vantages, which turned it into a releva......

Isochlorogenic acid B alleviates lead-induced anxiety, depression and neuroinflammation in mice by the BDNF pathway

期刊: NEUROTOXICOLOGY, 2023; 98 ()

Lead (Pb) can cause neurobehavioral abnormalities. Isochlorogenic acid B (ICAB), a dietary flavonoid found in tea, sweet potato, artichoke, propolis a......

Acute radiofrequency electromagnetic radiation exposure impairs neurogenesis and causes neuronal DNA damage in the young rat brain

期刊: NEUROTOXICOLOGY, 2023; 94 ()

A mobile phone is now a commonly used device for digital media and communication among all age groups. Young adolescents use it for longer durations, ......

Receptor protein tyrosine phosphatase 13/' regulates loss of neurogenesis in the mouse hippocampus following adolescent acute ethanol exposure

期刊: NEUROTOXICOLOGY, 2023; 94 ()

Adolescence is a critical period for brain maturation in which this organ is more vulnerable to the damaging effects of ethanol. Administration of eth......

Quantitative proteomics reveals the neurotoxicity of trimethyltin chloride on mitochondria in the hippocampus of mice

期刊: NEUROTOXICOLOGY, 2023; 99 ()

Trimethyltin chloride (TMT) is a potent neurotoxin widely used as a constituent of polyvinyl chloride plastic in the industrial and agricultural field......

Long-term LPS systemic administration leads to memory impairment and disturbance in astrocytic homeostasis

期刊: NEUROTOXICOLOGY, 2023; 99 ()

Dementia is the most prevalent neurodegenerative disorder, characterized by progressive loss of memory and cognitive function. Inflammation is a major......

Assessment of the neuroprotective effect of selenium-loaded chitosan nanoparticles against silver nanoparticles-induced toxicity in rats

期刊: NEUROTOXICOLOGY, 2023; 95 ()

Background: With the recent growth in the applications of silver nanoparticles (Ag-NPs), worries about their harmful effects are increasing. Selenium ......

Friedelin and Glutinol induce neuroprotection against ethanol induced neurotoxicity in pup's brain through reduction of TNF-α, NF-kB, caspase-3 and PARP-1

期刊: NEUROTOXICOLOGY, 2023; 99 ()

Ethanol administration triggers an inflammatory response that leads to a complex series of immune responses including the release of an excessive amou......

Heterozygous disruption of beclin 1 alleviates neurotoxicity induced by sub-chronic exposure of arsenite in mice

期刊: NEUROTOXICOLOGY, 2023; 94 ()

Arsenite is a well-documented neurotoxicant that widely exists in the environment. However, the detailed mechanisms of arsenite neurotoxicity are not ......

Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21-5p/SOCS6 pathway

期刊: NEUROTOXICOLOGY, 2023; 95 ()

Alzheimer's disease (AD) is a neurodegenerative disorder with progressive memory loss in dementia. Gold nanoparticles (AuNPs) were reported beneficial......

Kainic acid induced hyperexcitability in thalamic reticular nucleus that initiates an inflammatory response through the HMGB1/TLR4 pathway

期刊: NEUROTOXICOLOGY, 2023; 95 ()

Objective: To explore the relationship between the proinflammatory factor high-mobility group box 1 (HMGB1) and glutamatergic alpha-amino-3-hydroxy-5-......

Clinical significance of fractional anisotropy in cerebral white matter regional vulnerability caused by carbon monoxide poisoning: A systematic review and meta-analysis

期刊: NEUROTOXICOLOGY, 2023; 96 ()

Carbon monoxide poisoning (COP) can lead to various cerebral white matter (WM) lesions across different disease phases and clinical manifestations, an......

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