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The importance of the endothelial nitric oxide synthase on the release of 6-nitrodopamine from mouse isolated atria and ventricles and their role on chronotropism

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 138 ()

6-nitrodopamine (6-ND) is released from rat isolated atria, where it acts as a potent positive chronotropic agent. The release of 6-ND from rat isolat......

The role of nitric oxide (NO) modulators in obsessive-compulsive disorder (OCD)

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 134 ()

Obsessive-compulsive disorder (OCD) is as serious devastating anxiety disorder. Selective serotonin reuptake inhibitors (SSRIs) are largely used for t......

Transdermal iontophoretic application of L-NAME is available in sweating research induced by heat stress in young healthy adults

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 138 ()

Iontophoretic transdermal administration of NG-nitro-L-arginine methyl ester hydrochloride [L-NAME, a nitric oxide synthase (NOS) inhibitor] has been ......

Glu298Asp variant of the endothelial nitric oxide synthase gene and acute coronary syndrome or premature coronary artery disease: A systematic review and meta-analysis

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 138 ()

Introduction: Several published studies have reported an association between the Glu298Asp polymorphism (rs1799983), residing in the endothelial nitri......

Hydrogen sulfide: From a toxic gas to a potential therapy for COVID-19 and inflammatory disorders

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 140 ()

COVID-19 has been shown to induce inflammatory disorders and CNS manifestations. Swift and efficient treatment strategies are urgently warranted for t......

L-Arginine/nitric oxide pathway and oxidative stress in adults with ADHD: Effects of methylphenidate treatment

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 138 ()

Introduction: Attention deficit hyperactivity disorder (ADHD) is a mental disorder that was once thought to occur only in children. Meanwhile, it is k......

Gaseous nitric oxide failed to inhibit the replication cycle of SARS-CoV-2 in vitro

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 132 ()

Nitric oxide (NO) has been shown to have antimicrobial activity in vitro and in some in vivo models, while the virucidal activity of NO remains elusiv......

Nitric oxide mediated hypoxia dynamics in COVID-19

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 133 ()

Several COVID-19 patients frequently experience with happy hypoxia. Sometimes, the level of nitric oxide (NO) in COVID-19 patients was found to be gre......

Nitric oxide: An emerging warrior of plant physiology under abiotic stress

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 140 ()

The natural environment of plants comprises a complex set of various abiotic stresses and their capability to react and survive under this anticipated......

Heterogenous improvements in endothelial function by sub-blood pressure lowering doses of ARBs result in major anti-aortic root remodeling effects

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 131 ()

Low basal nitric oxide (NO) production is associated with a dysfunctional endothelium and vascular diseases. We have shown that some angiotensin II (A......

The effect of orally administered nitrate on renal function and blood pressure in a randomized, placebo-controlled, crossover study in healthy subjects

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 134 ()

Background: Several studies have shown inorganic nitrate/nitrite to reduce blood pressure in both healthy subjects and hypertensive patients. An effec......

Dietary nitrate supplementation increases nitrate and nitrite concentrations in human skin interstitial fluid

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 134 ()

Acute dietary nitrate (NO3-) supplementation can increase [NO3-], but not nitrite ([NO2-]), in human skeletal muscle, though its effect on [NO3-] and ......

Synthesis and secretion of Nerve Growth Factor is regulated by Nitric Oxide in bladder cells in vitro under a hyperglycemic environment

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 140 ()

Urine samples of female patients with overactive bladder (OAB) are characterized by low levels of nerve growth factor (NGF) and elevated concentration......

Phytochemicals targeting nitric oxide signaling in neurodegenerative diseases

期刊: NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2023; 130 ()

Neurodegenerative diseases are a set of diseases in which slow and progressive neuronal loss occurs. Nitric oxide (NO) as a neurotransmitter performs ......

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