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Abnormal expression of MAPK14-related lncRNAs in the peripheral blood of patients with multiple sclerosis

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

Introduction: Contribution of MAPK14 in the pathogenesis of multiple sclerosis (MS) has been proposed by several studies. Long non-coding RNA (lncRNA)......

miRNA-1246, HOTAIR, and IL-39 signature as potential diagnostic biomarkers in breast cancer

期刊: NON-CODING RNA RESEARCH, 2023; 8 (2)

The molecular alterations in noncoding RNA can lead to a cellular storm that is correlated to higher mortality and morbidity rates and contributes to ......

MicroRNA-122 mimic/microRNA-221 inhibitor combination as a novel therapeutic tool against hepatocellular carcinoma

期刊: NON-CODING RNA RESEARCH, 2023; 8 (1)

Background: Therapeutic microRNAs (miRNAs) delivery holds a lot of promise for treating human malignancies. So, this study was carried out to examine ......

Immunologic response in patients with polytrauma

期刊: NON-CODING RNA RESEARCH, 2023; 8 (1)

Purpose: It is now known that traumatic injury initiates a complex and dynamic immune response on the first day. It is believed that in patients with ......

Letter to editor regarding piR-36249 and DHX36 together inhibit testicular cancer cells progression by upregulating OAS2

期刊: NON-CODING RNA RESEARCH, 2023; 8 (4)

Several reports describing PIWI-interacting RNAs (piRNAs) in human cancer cells or in the bloodstream are affected by the presence of false positives ......

Firalink: A bioinformatics pipeline for long non-coding RNA data analysis

期刊: NON-CODING RNA RESEARCH, 2023; 8 (4)

: The Firalink bioinformatics pipeline has been developed to analyse long non-coding RNA (lncRNA) data generated by targeted sequencing. This pipeline......

LncRNAs NEAT1, HOTAIR, and GAS5 expression in hypertensive and non-hypertensive associated cerebrovascular stroke patients, and its link to clinical characteristics and severity score of the disease

期刊: NON-CODING RNA RESEARCH, 2023; 8 (1)

Background: Cerebrovascular stroke (CVS) is a potentially fatal disease. The most common risk factor for CVS is hypertension. Aim: While most studies ......

MicroRNA miR-214-5p induces senescence of microvascular endothelial cells by targeting the JAG1/Notch signaling pathway

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

During cellular senescence, irreversible cell cycle arrest is accompanied by morphological and genetic alterations. MicroRNAs (miRNAs) play a critical......

Exosomal non-coding RNAs: Blueprint in colorectal cancer metastasis and therapeutic targets

期刊: NON-CODING RNA RESEARCH, 2023; 8 (4)

Colorectal cancer (CRC) is ranked as the world's third-most prevalent cancer, and metastatic CRC considerably increases cancer-related fatalities glob......

Lnc-HULC, miR-122, and sirtulin-1 as potential diagnostic biomarkers for psoriasis and their association with the development of metabolic syndrome during the disease course

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

Psoriasis is a persistent inflammatory skin disorder driven by T cells. The disease is characterized by aberrant keratinocytes (KCs) differentiation, ......

Diagnostic potential and pathogenic performance of circulating miR-146b , miR-194, and miR-214 in liver fibrosis

期刊: NON-CODING RNA RESEARCH, 2023; 8 (4)

Liver fibrosis is the excessive accumulation of extracellular matrix proteins. Due to the lack of an accurate test for an early diagnosis of liver fib......

Telomerase RNA component lncRNA as potential diagnostic biomarker promotes CRC cellular migration and apoptosis evasion via modulation of ?-catenin protein level

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

Aim: Long non-coding RNA (LncRNA) telomerase RNA component (TERC) has telomerase-dependent and independent activity in numerous cancer types. The pres......

The intracellular parasite Anncaliia algerae induces a massive miRNA down-regulation in human cells

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

Anncaliia algerae belongs to microsporidia, a group of obligate intracellular parasites related to fungi. These parasites are largely spread in water ......

Salivaomics to decode non-coding RNAs in oral cancer. A narrative review

期刊: NON-CODING RNA RESEARCH, 2023; 8 (3)

Oral cancer is the most debilitating disease which affects the orderly life of a human. With so much advancement in research and technology, the avera......

microRNA hsa-miR-425-5p and hsa-miR-4523 expressions as biomarkers of active pulmonary tuberculosis, latent tuberculosis infection, and lymph node tuberculosis

期刊: NON-CODING RNA RESEARCH, 2023; 8 (4)

Background: Studies on miRNA highlight its significance as an immunomarker for several diseases, including tuberculosis. This study aimed to determine......

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