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Screening of core genes and prediction of ceRNA regulation mechanism of circRNAs in nasopharyngeal carcinoma by bioinformatics analysis

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Background: Nasopharyngeal carcinoma (NPC) represents a highly aggressive malignant tumor. Competing endogenous RNAs (ceRNA) regulation is a common re......

Immunohistochemistry-based molecular subtyping of triple-negative breast cancer and its prognostic significance

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Background: Immunohistochemistry (IHC)-based protein markers representing molecular subtypes are of great value for routine use. This study aimed to e......

Urachus adenocarcinoma mistaken for umbilical incision implant cancer after laparoscopic cholecystectomy: a case report

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Umbilical incision implant cancer after LC is rare. Elective cholecystectomy was planned for a 49 years-old female patient with symptomatic gallstones......

Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Several reports indicate that apelin is often over-expressed in tumors, and therefore it has been suggested that the apelin-apelin receptor (APJ) syst......

Tumor budding as a predictor of disease-free survival in patients with cholangiocarcinoma

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Background: Tumor budding is considered a prognostic factor in several solid cancer types. However, we lack comprehensive information on the importanc......

Case report: Large-size intramuscular nodular fasciitis, a challenging histopathologic diagnosis confirmed by molecular detection of USP6 gene rearrangement: Case report and literature review

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

The intramuscular subtype of nodular fasciitis (NF) is rare with lesions normally not more than 2 cm in size and characterized by pseudosarcomatous mo......

Development and validation of a prognostic nomogram for rectal cancer patients who underwent surgical resection

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Objective: The purpose of this study was to develop and validate a nomogram model for the prediction of survival outcome in rectal cancer patients who......

Influence of the microbiota on the effectiveness and toxicity of oncological therapies, with a focus on chemotherapy

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Recent studies have highlighted a possible correlation between microbiota composition and the pathogenesis of various oncological diseases. Also, many......

Tumor PD-L1 expression and molecular profiling are not associated with immune checkpoint inhibitor-induced thyroid dysfunction in advanced NSCLC patients

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Background: Immune-checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced non-small cell lung cancer (NSCLC), however are frequent......

A new perspective on the proper timing of radiotherapy during CDK4/6 inhibitor therapy in patients with bone-only metastatic breast cancer

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

The vast majority of hormone positive and HER2 negative advanced breast cancers can be controlled well by endocrine therapy combined with the groundbr......

Case report: Squamous cell carcinoma of the prostate-a clinicopathological and genomic sequencing-based investigation

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Squamous differentiation of prostate cancer, which accounts for less than 1% of all cases, is typically associated with androgen deprivation treatment......

Grade Group accuracy is improved by extensive prostate biopsy sampling, but unrelated to prostatectomy specimen sampling or use of immunohistochemistry

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Assessing the accurate Grade Group of a prostate needle biopsy specimen is essential for choosing the adequate therapeutic modality for prostate cance......

Single-cell transcriptome analysis reveals the clinical implications of myeloid-derived suppressor cells in head and neck squamous cell carcinoma

期刊: PATHOLOGY & ONCOLOGY RESEARCH, 2023; 29 ()

Head and neck squamous cell carcinoma (HNSC) is the most common malignant tumor that arises in the epithelium of the head and neck regions. Myeloid-de......

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