期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (5)
Emicizumab has been widely used for prophylaxis in patients with hemophilia A (HA) of all ages, with or without factor VIII inhibitors. Data on emiciz......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (6)
MicroRNA-199a (miR-199a) inhibits the progression of several hematological malignancies and enhances the sensitivity to chemotherapy in acute myeloid ......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (6)
6-mercaptopurine (6-MP) plays a critical role in the treatment of pediatric acute lymphoblastic leukemia (ALL). NUDT15 and TPMT gene variants have bee......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (6)
In pediatric cancer care, medication non-adherence is a significant driver of avoidable suffering and death. There is a lack of interventions designed......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (2)
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation. It occurs because of severe inflammation due to uncontrolled p......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (3)
Childhood cancer survivors (CCS) experience short- and long-term side effects from cancer treatment that often impair functional capacity. Inspiratory......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (2)
Emerging evidence suggests that KIF11 could play a pivotal role in cancer cell proliferation; however, its biological functions and molecular mechanis......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (6)
Children with underlying cancer are often immunocompromised. Data on severity of coronavirus disease 2019 (COVID-19) in children with cancer and its o......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (7)
Racial and ethnic inequities in survival persist for children with acute lymphoblastic leukemia (ALL). In the US, there are strong associations betwee......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (3)
Rhabdoid tumors (RTs) are a rare and aggressive pediatric cancer that commonly presents with alterations in the tumor suppressor gene SMARCB1. However......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (5)
Pediatric B-cell lymphoblastic lymphoma (LBL) is a rare entity, and appropriate treatment for pediatric B-cell LBL is not well defined. While intensiv......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (1)
Survivin is an inhibitor of apoptosis protein that inhibits caspases and blocks cell death. It is undetectable in most normal adult tissues. High surv......
期刊: PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2022; 39 (3)
Methotrexate containing chemotherapy is less commonly used for treatment of osteosarcoma in resource limited settings. We present our experience with ......