期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
For the increasing number of type 1 diabetes in Japan, after 1960, a greater supply of insulin was required, accordingly the availability of insulin g......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
Globally it is estimated that over 1 million children and adolescents have Type 1 diabetes with large variations in incidence between different contex......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
Epidemiological data on pediatric type 1 diabetes (T1D), mainly incidence, have become increasingly available since the second half of the 20th centur......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
Both in vitro and in vivo experimental studies proved that insulin has on important anabolic role. This physiological function of insulin is reflected......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
The negative consequencies of diabetes treatment are traditionally regarded as caused by a disastrous treatment rather than adverse events of the insu......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
For people with type 1 diabetes, achieving optimal glycemic control requires use of intensive insulin therapy. To achieve this goal individuals are re......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
A(most a century ago, the first insulin was produced by Banting, Best, MacLeod and Collip in Toronto, thereby enabling life-saving treatment for peopl......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
Eli Lilly and Company has played a pivotal role in the development of insulin products since its discovery in 1921. Through their dedication to pharma......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2020; 17 ()
The isolation and purification of insulin nearly 100 years ago has been one of the most ground-breaking discoveries in the history of medicine. Subseq......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2019; 16 (3)
Major difficulties reported by endocrinologists / pediatricians / hematologists in the care of thalassemic patients with endocrine complications were:......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2019; 16 (3)
Thirty-one scientists met at Aschauhof, Germany to discuss the role of beliefs and self-perception on body size. In view of apparent growth stimulator......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2019; 16 (3)
Introduction Infertility is a major concern for females with Turner syndrome (TS), regardless of their age. While fertility preservation is now routin......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2019; 16 (3)
Due to well-designed studies of birth cohorts and at-risk individuals, our understanding of the natural history of pre- and early type 1 diabetes (TID......
期刊: PEDIATRIC ENDOCRINOLOGY REVIEWS PER, 2019; 16 (3)
Apparent mineralocorticoid excess (AME) is a rare inherited disorder caused by pathogenic variants in the 11B-HSD2 gene resulting in a deficiency of t......