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Pharmacogenomics implementation across multiple clinic settings: a qualitative evaluation

期刊: PHARMACOGENOMICS, 2023; 24 (17)

Aim: To advance clinical adoption and implementation of pharmacogenomics (PGx) testing, barriers and facilitators to these efforts must be understood.......

Pharmacogenomic testing in oncology: a health system's approach to identify oncology provider perspectives

期刊: PHARMACOGENOMICS, 2023; 24 (16)

Aim: Identify oncology healthcare providers' attitudes toward barriers to and use cases for pharmacogenomic (PGx) testing and implications for prescri......

Attitudes about pharmacogenomic testing vary by healthcare specialty

期刊: PHARMACOGENOMICS, 2023; 24 (10)

Aim: To understand how attitudes toward pharmacogenomic (PGx) testing among healthcare providers varies by specialty. Methods: Providers reported comf......

Effect of pharmacogenomic testing on pediatric mental health outcome: a 6-month follow-up

期刊: PHARMACOGENOMICS, 2023; 24 (2)

Aim: This retrospective, case-control study evaluated the effect of pharmacogenomic testing (PGT) on the management of pediatrics with anxiety, major ......

Pharmacogenomics of oxcarbazepine in the treatment of epilepsy

期刊: PHARMACOGENOMICS, 2023; 24 (6)

Plain language summaryAs a new-generation aromatic antiepileptic drug, oxcarbazepine (OXC) is often used for epilepsy treatment. It is known that when......

Pharmacogenetics of 6-mercaptopurine in a black Zimbabwean cohort treated for acute lymphoblastic leukaemia

期刊: PHARMACOGENOMICS, 2023; 24 (8)

Plain language summaryAcute lymphoblastic leukemia (ALL) is the most common malignancy affecting children in Zimbabwe and 6-mercaptopurine is frequent......

Carbamazepine cutaneous adverse reactions and HLA gene variation in the Chinese population: a systematic review and meta-analysis

期刊: PHARMACOGENOMICS, 2023; 24 (8)

Aim: Examining the association between HLA-A/B alleles and different carbamazepine (CBZ)-induced cutaneous adverse reactions in the Chinese population......

The potential of exome sequencing of paired colorectal tumors and synchronous liver metastases to improve treatment

期刊: PHARMACOGENOMICS, 2023; ()

Sequencing exomes of synchronous and metachronous liver metastases of colorectal cancer has potential to enhance treatment, since they can have molecu......

Distribution of pharmacogene allele and phenotype frequencies in Brazilian psychiatric patients

期刊: PHARMACOGENOMICS, 2023; 24 (14)

Purpose: This work was designed to identify the pharmacogenetic profile of Brazilian psychiatric patients receiving psychoactive drug treatment accord......

Retrospective pharmacogenetic study in a cohort of pediatric tuberous sclerosis complex patients using everolimus

期刊: PHARMACOGENOMICS, 2023; 24 (15)

Aim: Tuberous sclerosis complex (TSC) is a rare disease that produces multisystemic disorders. Everolimus (EVR) is the only immunosuppressive drug app......

Breast cancer pharmacogenetics: a systematic review

期刊: PHARMACOGENOMICS, 2023; 24 (2)

Breast cancer was declared the most prevalent type of cancer in 2020. Among other factors, treatment response can be affected by genetic polymorphisms......

Pharmacogenetics of anxiety and depression in Alzheimer's disease

期刊: PHARMACOGENOMICS, 2023; 24 (1)

Anxiety and depression coexist with cognitive impairment in Alzheimer's disease along with other concomitant disorders (>60%), which require multip......

Association of OPRK1 rs963549 and rs997917 polymorphisms with opioid use disorder and the related phenotypes

期刊: PHARMACOGENOMICS, 2023; 24 (6)

Aim: To evaluate the association between OPRK1 rs963549 and rs997917 and opioid use disorder (OUD) and related phenotypes.Methods: A sample of 208 ind......

Pharmacogenetics of pain management in Zimbabwean patients with sickle cell disease

期刊: PHARMACOGENOMICS, 2023; 24 (7)

Background: Pain is a common cause of hospitalization in sickle cell disease (SCD) patients. Failure to effectively control pain remains a challenge i......

Application of next-generation sequencing in diffuse large B-cell lymphoma

期刊: PHARMACOGENOMICS, 2023; 24 (1)

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of invasive non-Hodgkin lymphoma. There is great heterogeneity in its molecular biolo......

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