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Mirtazapine attenuates the cocaine-induced locomotor sensitization in male and female C57BL/6J and BALBA/cJ mouse

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 222 ()

Background: Clinical studies have described the efficacy of various therapeutic approaches. Results are inconsistent and clinical application is limit......

Developmental treatments with?9-tetrahydrocannabinol and the MAGL inhibitor JZL184 persistently alter adult cocaine conditioning in contrasting ways

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 223 ()

Using a songbird, zebra finches, as a developmental drug abuse model we found previously that cannabinoid agonists administered during the sensorimoto......

Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 224 ()

Central ghrelin signaling seems to play important role in addiction as well as memory processing. Antagonism of the growth hormone secretagogue recept......

GRM7 gene mutations and consequences for neurodevelopment

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 225 ()

The metabotropic glutamate receptor 7 (mGlu7), encoded by the GRM7 gene in humans, is a presynaptic, G protein-coupled glutamate receptor that is esse......

Delay discounting as a behavioral phenotype associated with social rank in female and male cynomolgus monkeys: Correlation with kappa opioid receptor availability

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 225 ()

Cocaine use disorder (CUD) is a significant problem worldwide, with no FDA-approved treatments. Epidemiological data indicate that only about 17 % of ......

Postpartum scarcity-adversity inflicts sex-specific cerebellar adaptations and reward behaviors in adolescence

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 231 ()

Early life adversity in the form of poor postnatal care is a major developmental stressor impacting behavior later in life. Previous studies have show......

Interactions between estradiol and ERK, but not mTOR, signaling is necessary for enhanced cocaine-induced conditioned place preference in female rats

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 232 ()

Women rapidly progress from recreational cocaine use to dependence, consume greater quantities of cocaine, experience more positive subjective effects......

The intersection of empathy and addiction

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 222 ()

Empathy, the ability to perceive the affective state of another, is a complex process that is integral to many of the prosocial behaviors expressed in......

Differential patterns of opioid and dopamine D1 receptor antagonism on nutritive and non-nutritive sweetener intakes in C57BL/6:129 hybrid mice relative to inbred C57BL/6 and 129 mice

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 223 ()

Opioid and dopamine (DA) D1 receptor antagonists differentially reduce nutritive and non-nutritive sweetener intakes in inbred mouse strains. Sucrose ......

Early prenatal and late prenatal escitalopram exposure differentially impacts behavioral flexibility and anxiety-related behaviors in adulthood

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 224 ()

Selective serotonin reuptake inhibitors (SSRIs) are medications commonly used by pregnant women. While SSRIs have been considered safe during pregnanc......

Demand and cross-price elasticity of cocaine and social contact in a free-operant procedure of nonexclusive choice

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 222 ()

Research examining the social determinants of addiction has advanced significantly with the recent development of preclinical models of drug use and t......

CB1R chronic intermittent pharmacological activation facilitates amphetamine seeking and self-administration and changes in CB1R/CRFR1 expression in the amygdala and nucleus accumbens in rats

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 227 ()

Patterns of drug ingestion may have a dissimilar impact on the brain, and therefore also the development of drug addiction. One pattern is binge intox......

Role of social context in addiction etiology and recovery

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 229 ()

While social context has long been considered central to substance use disorder prevention and treatment and many drug-taking events occur in social s......

A pilot study examining the relationship between chronic heroin use and telomere length among individuals of African ancestry

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 231 ()

Background: Prior research has suggested a possible link between heroin use and shortened telomere length (TL), a marker of cellular aging and genomic......

iTat transgenic mice exhibit hyper-locomotion in the behavioral pattern monitor after chronic exposure to methamphetamine but are unaffected by Tat expression

期刊: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2023; 222 ()

Although antiretroviral therapy (ART) has increased the quality of life and lifespan in people living with HIV (PWH), millions continue to suffer from......

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