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Effects of Anesthesia Changes During Maintenance ECT: A Longitudinal Comparison of Seizure Quality Under Anesthesia Using Propofol/Esketamine Versus Methohexital

期刊: PHARMACOPSYCHIATRY, 2023; 56 (4)

Introduction The effectiveness of ECT relies on the induction of a generalized cerebral seizure. Among others, seizure quality (SQ) is potentially inf......

Revisiting the World's Strictest COVID-19 Lockdown: Formidable Mental Health Challenges

期刊: PHARMACOPSYCHIATRY, 2023; 56 (4)

Introduction Many nations have implemented lockdowns to prevent and minimize the spread of infections in healthcare settings. However, the impact of l......

Dexmedetomidine in Psychiatry: Repurposing of its Fast-Acting Anxiolytic, Analgesic and Sleep Modulating Properties

期刊: PHARMACOPSYCHIATRY, 2023; 56 (2)

Drug repurposing is a strategy to identify new indications for already approved drugs. A recent successful example in psychiatry is ketamine, an anest......

The Role of Mood Stabilizers in Children and Adolescents with Anorexia Nervosa: A 1-year Follow-Up, Propensity Score-Matched Study

期刊: PHARMACOPSYCHIATRY, 2023; 56 (3)

Background The existing literature on the use of mood stabilizers (MS) in children and adolescents with anorexia nervosa (AN) is limited, for the most......

Hippocampal Dysfunction in Schizophrenia and Aberrant Hippocampal Synaptic Plasticity in Rodent Model Psychosis: a Selective Review

期刊: PHARMACOPSYCHIATRY, 2023; 56 (2)

Schizophrenia is a complex, heterogeneous psychiatric disorder that affects about 1 % of the global population. Hippocampal dysfunction has been linke......

Effects of Early Clozapine Treatment on Remission Rates in Acute Schizophrenia (The EARLY Trial): Protocol of a Randomized-Controlled Multicentric Trial

期刊: PHARMACOPSYCHIATRY, 2023; 56 (5)

Background Quick symptomatic remission after the onset of psychotic symptoms is critical in schizophrenia treatment, determining the subsequent diseas......

Antipsychotic Monotherapy for Major Depressive Disorder: A Systematic Review and Meta-Analysis

期刊: PHARMACOPSYCHIATRY, 2023; 56 (1)

Although several randomized controlled trials (RCTs) have compared the effectiveness, efficacy, and safety of antipsychotic monotherapy (APM) versus p......

Interpersonal Needs, Mental Pain, and Hopelessness in Psychiatric Inpatients with Suicidal Ideation

期刊: PHARMACOPSYCHIATRY, 2023; 56 (6)

Introduction Suicide is a leading cause of death worldwide and models may help the understanding of the phenomenon and ultimately reduce its burden th......

Serious Adverse Drug Reactions to Antipsychotics in Minors with Multiple Disabilities: Preventability and Potential Cost Savings by Therapeutic Drug Monitoring

期刊: PHARMACOPSYCHIATRY, 2023; 56 (1)

Introduction Children and adolescents with multiple disabilities and mental disorders (CAMD) are frequently treated with antipsychotic drugs. However,......

Circadian Clocks in the Regulation of Neurotransmitter Systems

期刊: PHARMACOPSYCHIATRY, 2023; 56 (3)

To anticipate and adapt to daily recurring events defined by the earth's rotation such as light-dark and temperature cycles, most species have develop......

Synchronization of Fibroblasts Ex Vivo in Psychopharmacology

期刊: PHARMACOPSYCHIATRY, 2023; 56 (3)

The central oscillator for the inner clock is the suprachiasmatic nuclei of the hypothalamus. Furthermore, many peripheral oscillators are present in ......

Linkage of Young Mania Rating Scale to Clinical Global Impression Scale to Enhance Utility in Clinical Practice and Research Trials

期刊: PHARMACOPSYCHIATRY, 2023; 56 (1)

Introduction The Young Mania Rating Scale (YMRS) is the gold standard to assess manic symptoms of bipolar disorder, yet the clinical meaning of scores......

Prevalence of COVID-19 and Psychotropic Drug Treatment in Psychiatric In-patients in Germany in 2020: Results from a Nationwide Pilot Survey

期刊: PHARMACOPSYCHIATRY, 2023; 56 (6)

Introduction In patients with a pre-existing mental disorder, an increased risk for a first manifestation of a psychiatric disorder in COVID-19 patien......

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